The study shows that the key problems in the training of specialists in interdisciplinary areas are the lack of shared understanding of the content of professional competencies and a variety of requests for knowledge and skills of graduates. For interdisciplinary educational programs, such as Business Informatics and Applied Informatics in the economy, the problem is aggravated by the fact that the rapid development of information technologies leads to a constant change in the requirements of employers. To solve these problems, universities need mechanisms for constant adaptation of educational programs to the labor market in a digital environment. The conducted investigation allows to distinguish the following mechanisms: design of educational standards taking into account professional standards, professional and public accreditation, councils of educational programs, questioning of graduates and employers, participation of employers at all stages of the educational process. Due to the lack of effective procedures for the use of these mechanisms, they are often applied formally. The paper presents the procedures for the implementation of these mechanisms, tested for five years in the process of constant improvement of bachelor and master programs in "Business Informatics" at Saint Petersburg State University. The proposed procedures can be successfully replicated for other universities regarding their specifics.