Research output: Contribution to journal › Article › peer-review
Когнитивные нарушения у пациентов с биполярным аффективным расстройством в ремиссии. / Чумаков, Егор Максимович; Петрова, Наталия Николаевна; Лиманкин, Олег Васильевич; Ашенбреннер, Юлия Владимировна.
In: ЖУРНАЛ НЕВРОЛОГИИ И ПСИХИАТРИИ ИМ. C.C. КОРСАКОВА, Vol. 121, No. 4, 2021, p. 12-18.Research output: Contribution to journal › Article › peer-review
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TY - JOUR
T1 - Когнитивные нарушения у пациентов с биполярным аффективным расстройством в ремиссии
AU - Чумаков, Егор Максимович
AU - Петрова, Наталия Николаевна
AU - Лиманкин, Олег Васильевич
AU - Ашенбреннер, Юлия Владимировна
PY - 2021
Y1 - 2021
N2 - Objective. To assess the frequency and severity of cognitive impairment as well as its correlations with clinical characteristics in remitted patients with bipolar disorder (BD). Material and methods. Eighty-five patients with BD type I (64 patients) and BD type II (21 patients) in remission were examined (average age 36.6±5.7). Affective symptoms were assessed using the Hamilton Depression Rating Scale (HDRS) and Young’s Mania Rating Scale (YMRS). Cognitive impairment was assessed using the Brief Neuropsychological Cognitive Examination (BNCE). Results. Cognitive impairment was revealed in 43.5% of the patients. The frequency and structure of cognitive impairment in patients with BD type I and type II did not differ. The patients with cognitive impairment were characterized by decreased speed of mental processes, decreased working memory and attention deficit. The correlation of the total BNCE score with the age of the pa-tients, duration of the disease, total HDRS and YMRS scores was revealed. Conclusion. The results demonstrate the affective nature of cognitive deficit in the patients. Cognitive impairment in remitted patients with BD is a significant therapeutic target.
AB - Objective. To assess the frequency and severity of cognitive impairment as well as its correlations with clinical characteristics in remitted patients with bipolar disorder (BD). Material and methods. Eighty-five patients with BD type I (64 patients) and BD type II (21 patients) in remission were examined (average age 36.6±5.7). Affective symptoms were assessed using the Hamilton Depression Rating Scale (HDRS) and Young’s Mania Rating Scale (YMRS). Cognitive impairment was assessed using the Brief Neuropsychological Cognitive Examination (BNCE). Results. Cognitive impairment was revealed in 43.5% of the patients. The frequency and structure of cognitive impairment in patients with BD type I and type II did not differ. The patients with cognitive impairment were characterized by decreased speed of mental processes, decreased working memory and attention deficit. The correlation of the total BNCE score with the age of the pa-tients, duration of the disease, total HDRS and YMRS scores was revealed. Conclusion. The results demonstrate the affective nature of cognitive deficit in the patients. Cognitive impairment in remitted patients with BD is a significant therapeutic target.
KW - Bipolar disorder
KW - Cognitive impairment
KW - Remission
KW - Residual symptoms
UR - http://www.scopus.com/inward/record.url?scp=85107085803&partnerID=8YFLogxK
UR - https://www.mendeley.com/catalogue/f4459bbb-208f-391b-ae0f-d3c7b2e2db71/
U2 - 10.17116/jnevro202112104112
DO - 10.17116/jnevro202112104112
M3 - статья
VL - 121
SP - 12
EP - 18
JO - ЖУРНАЛ НЕВРОЛОГИИ И ПСИХИАТРИИ ИМ. C.C. КОРСАКОВА
JF - ЖУРНАЛ НЕВРОЛОГИИ И ПСИХИАТРИИ ИМ. C.C. КОРСАКОВА
SN - 1997-7298
IS - 4
ER -
ID: 74272279