The paper presents the results of an empirical study, which purpose was to study the relationship between the perception of everyday stressors and the functional state of the nervous system, the level of stress tension and personal characteristics. The study was performed on a sample (n = 120) at the age of 20 to 60 years old (50% of men and 50% of women) with the use of a complex of psychodiagnostic instruments: for the study of everyday life stressors the author’s questionnaire including 82 stressful events was used; for assessment of the operability and functional state of the CNS was used a computer technique by M. P. Moroz (2001); the level of stress intensity was determined using the questionnaire «ShVS-10» (by V. A. Ababkov et al); for the study of personal variables, a 16-factor questionnaire by R. Cattell (adapted by A. N. Kapustin), a questionnaire of USC by J. Rotter (adapted by E. F. Bazhin et al.) were used. An expressed level of perceived everyday stressors has been revealed in all the spheres of life under consideration. The expressed stress load was manifested in a decrease in the performance level of nervous system and in the increase of psychological tension. It has been established that an increase in anxiety, a decrease in self-control and an increase in externality contribute to the perception and evaluation of the most of events as stressful. Significant differences in the structures of the relationship between physiological and psychological indicators of stress tension and personality characteristics between groups of subjects with different levels of performance of the nervous system are revealed. In the group with the normative level of the functional state of the CNS, a greater integration of all the studied parameters was found than that in the group with reduced performance. This may indicate that a higher level of integration of all indicators is a factor in counteracting everyday stressors and is ensured by the optimalnormative functional state of the CNS. The reduced functional level of the CNS and the disintegration of personality traits and indicators of tension contribute to the perception of the most of events as stressful.