Introduction. The article discusses the issues of psychological counseling in oncological clinic using the example of psychological care for patients with bone tumors. Purpose: to formulate the main directions of psychological counseling in an oncoortopedic clinic based on the results of empirical research and analysis of scientific literature. Methods: review and analysis of scientific literature devoted to the problem of psychological counseling of patients with bone tumors. The materials were collected and analyzed in open information resources: SCOPUS, Google Scholar, Springer, PubMed. Results: The level and features of quality of life in patients with oncoortopedic pathology, in addition to clinical factors, are largely determined by psychological factors, the leading ones are personality characteristics and life satisfaction in conditions of the disease. In this regard, the main “target” of clinical and psychological interventions in oncoortopedic clinic is quality of life in patients, integrating objective limitations of functional capabilities in conditions of illness and their subjective perception, the totality of patient’s experiences and relationships, understanding their own existence, values of health and ability to establish relationships with the outside world in accordance with their needs and individual capabilities. Conclusion: the overall goal of psychological counseling in oncoortopedic clinic can be considered as changing in cognitive, emotional and behavioral characteristics affecting patient’s quality of life: formation of understanding of the current situation and adequate self-understanding, correction of emotional state and emotional relationships, changing maladaptive behavioral stereotypes.