The article on the materials of the All-Russian population census of 2010 discusses the features of the age and gender structure of the Uzbek population of St. Petersburg. The main factor determining the demographic and social parameters of the Uzbek diaspora of the city has been the massive influx of guest workers to St. Petersburg from Central Asia since the early 2000s. The features of the professional structure of Uzbek labor migrants determined the unevenness of their resettlement throughout the territory of St. Petersburg.