TY - JOUR

T1 - ЛЮМИНЕСЦЕНЦИЯ ПРОЧНОСВЯЗАННЫХ СТОПОЧНЫХ АГРЕГАТОВ АДЕНИНА И УРАЦИЛА В ВОДЕ

AU - Pапопоpт, В.Л.

AU - Малкин, В.М.

AU - Cавина, А.В.

AU - Cафаpгалеева, Е.А.

AU - Гоpючко, В.В.

PY - 2012

Y1 - 2012

N2 - Luminescence and excitation spectra of the highly luminescent stacking dimers of adenine and uracil in water solutions are studied. By the luminescence excitation spectra, it is shown that the stacking aggregates of adenine and uracil are formed with participation of rare forms of monomers: adenine N7H tautomers, and uracil in uncommon hydration states, e.g. lacking H-bonds with water. The temperature dependence of luminescence intensity of monomers and stacking dimers of uracil shows that stacking dimers do not dissociate even at 85°C, just as described earlier for adenine and adenosine. Stable stacking aggregates of nucleic bases are the likely precursors of RNA molecules in chemical evolution. This hypothesis is supported by new data on their heat stability.

AB - Luminescence and excitation spectra of the highly luminescent stacking dimers of adenine and uracil in water solutions are studied. By the luminescence excitation spectra, it is shown that the stacking aggregates of adenine and uracil are formed with participation of rare forms of monomers: adenine N7H tautomers, and uracil in uncommon hydration states, e.g. lacking H-bonds with water. The temperature dependence of luminescence intensity of monomers and stacking dimers of uracil shows that stacking dimers do not dissociate even at 85°C, just as described earlier for adenine and adenosine. Stable stacking aggregates of nucleic bases are the likely precursors of RNA molecules in chemical evolution. This hypothesis is supported by new data on their heat stability.

KW - chemical evolution

KW - stacking aggregates

KW - luminescence.

U2 - 10.1134/S0006350912010162

DO - 10.1134/S0006350912010162

M3 - статья

VL - 57

SP - 14

EP - 20

JO - БИОФИЗИКА

JF - БИОФИЗИКА

SN - 0006-3029

IS - 1

ER -