Breast cancer (BC) is the most common malignant tumor among women. New technologies and BC screening have led to early detection of the disease over the past two decades. As a result, percutaneous minimally invasive techniques (PMIT) are increasingly being considered to treat patients who are unsuitable for surgery, as well as women who refuse surgery or elderly patients with significant comorbidities for whom surgery may be a life-threatening treatment option. The main candidates for PMIT are patients with small-sized earlystage BC. The main aim of these techniques is to achieve an equally effective treatment outcome as standard surgery. Minimally invasive treatments offer a convenient alternative with promising efficacy, lower cost, less scarring and pain, and more satisfactory cosmetic results. Ablative techniques used for BC are cryoablation, radiofrequency ablation, microwave ablation, high-intensity focused ultrasound (HIFU), and laser ablation. This article aims to discuss various PMIT in the treatment of BC, to evaluate their clinical outcomes and to analyze the future prospects of ablation therapy in BC treatment.