The article presents the data of a complex analysis of the course of the early period of the newborn in children born to 456 women who were delivered in the maternity hospitals of St. Petersburg and the Leningrad Region in 2009-2016. These patients were divided into the main group (99 women who gave birth to live children who died in the first 7 days of life) and a comparison group (357 women who gave birth to live children who survived the first 7 days). Estimated the duration of pregnancy at the time of delivery, clinical features of newborn children in the group of patients with perinatal losses, in comparison with the control group, were analyzed. The article compares the anthropometric data of newborns (weight and height at birth), Apgar scores, and the frequency of fetal hypotrophy. The results of the clinical analysis of the blood of newborn children of the patients of the main and control groups (hemoglobin, erythrocytes, leukocytes, platelets and venous blood glucose) were also evaluated. A number of significant differences in the main group and comparison group that can be regarded as predictors of perinatal fetal death have been identified. Thus, the risk group for perinatal fetal death includes preterm newborns with hypotrophy, low body weight, smaller body length, a low Apgar score, changes in the clinical analysis of blood (lowering of hemoglobin, erythrocytes and platelets, and an increase in the level of venous blood glucose). The level of leukocytes in peripheral blood in newborns in both groups is not significantly different. (For citation: Ivanova LA, Titkova EV. Сlinical features of newborn children in patients with perinatal losses. Pediatrician (St. Petersburg). 2018;9(2):16-21. doi: 10.17816/PED9216-21).