The aim of the study was a clinical and functional assessment of residual symptoms, functional status, quality of life of patients in remission with recurrent depression. 52 patients were examined, 50.0 % met the criterion of complete remission. Regardless of the type of remission, functional disorders and a decrease in cognitive functions are detected. Patients with incomplete remission are characterized by moderate functional impairment, a decrease in the mental component of the quality of life, and a greater number of cognitive impairments. Thus, socio-functional maladaptation of patients with remission is revealed. For a differentiated assessment of the condition of patients and individualization of outpatient treatment and rehabilitation care, it is necessary to assess the level of residual symptoms, quality of life, functional state, and cognitive functions.