We recorded contrast sensitivity in normal and schizophrenic patients. We presented Gabor gratings with sinusoidal distribution of brightness, with the spatial frequency: 0.4 cycles/degree, 3.6 and 17.9 cycles/degree. Taken together patients with schizophrenia compared to the healthy subjects showed a decline of contrast sensitivity at low and medium spatial frequencies. We measured the influence of duration of illness and type of treatment on contrast sensitivity. Patients with schizophrenia less than 10 years, showed a decrease of contrast sensitivity only at low spatial frequencies, while patients suffered with schizophrenia for more than 10 years--at low, medium and high spatial frequencies. Persons with schizophrenia less than 10 years receiving treatment with atypical antipsychotics, show a decrease in contrast sensitivity at low spatial frequencies, while treated with typical antipsychotics--in the low and high spatial frequencies.

Translated title of the contributionThe contrast sensitivity in schizophrenia with different durations disease
Original languageRussian
Pages (from-to)928-936
Number of pages9
JournalРОССИЙСКИЙ ФИЗИОЛ. ЖУРНАЛ ИМ. И.М.СЕЧЕНОВА
Volume99
Issue number8
StatePublished - 1 Aug 2013

    Scopus subject areas

  • Medicine(all)

ID: 38413997