The aim was to study the indicators of quality of life of the adult population of the Chukotka Autonomous Region (ChAO) and to identify characteristics specific to the remote arctic area. Methods: The study included 424 residents of the Chukotka Autonomous Region aged 18 to 77 years old (231 - women and 193 - men). Using the RAND SF-36 questionnaire, health-related quality of life indicators were evaluated. Results: The average indicators of the life quality of Chukotka population were the following: physical functioning - 87.1 ± 17.9 points; role-physical functioning - 79.0 ± 32.1 points; pain index - 76.2 ± 23.3 points; general health - 63.9 ± 20.0 points; viability - 65.1 ± 18.1 points; social functioning - 81.7 ± 19.3 points; role-emotional functioning - 79.9 ± 31.1 points; mental health - 69.7 ± 16.9 points. The life quality of women was significantly lower than that of men according to the following scales: physical functioning (84.0 versus 90.1 points), role-physical functioning (75.2 versus 82.6 point