Research output: Contribution to journal › Article › peer-review
Вортиоксетин: от механизмов действия к клинике. / Петрова, Наталия Николаевна; Мухин, А.А.
In: ЖУРНАЛ НЕВРОЛОГИИ И ПСИХИАТРИИ ИМ. C.C. КОРСАКОВА, Vol. 122, No. 6 Vyp 2, 2022, p. 84-90.Research output: Contribution to journal › Article › peer-review
}
TY - JOUR
T1 - Вортиоксетин: от механизмов действия к клинике
AU - Петрова, Наталия Николаевна
AU - Мухин, А.А.
PY - 2022
Y1 - 2022
N2 - The opinion article is devoted to the analysis of a large-scale comprehensive systematic review of relevant and practically oriented studies of vortioxetine use in depression for the period to 2020. The mechanisms of multimodal action, issues of efficacy and safety of the drug, including direct procognitive effects, effects on anhedonia, anxiety, sleep disorders, analgesic and anti-inflammatory effects are highlighted. An increase in the efficacy of vortioxetine when the dose is increased to 20 mg/day is emphasized. Prospective directions for antidepressant research are outlined.
AB - The opinion article is devoted to the analysis of a large-scale comprehensive systematic review of relevant and practically oriented studies of vortioxetine use in depression for the period to 2020. The mechanisms of multimodal action, issues of efficacy and safety of the drug, including direct procognitive effects, effects on anhedonia, anxiety, sleep disorders, analgesic and anti-inflammatory effects are highlighted. An increase in the efficacy of vortioxetine when the dose is increased to 20 mg/day is emphasized. Prospective directions for antidepressant research are outlined.
KW - clinical efficacy
KW - mechanisms of action
KW - tolerability
KW - vortioxetine
KW - clinical efficacy
KW - mechanisms of action
KW - tolerability
KW - vortioxetine
UR - http://www.scopus.com/inward/record.url?scp=85134360471&partnerID=8YFLogxK
UR - https://www.mendeley.com/catalogue/1b78c8b4-fc93-366e-a040-dc69235fda6a/
U2 - 10.17116/jnevro202212206284
DO - 10.17116/jnevro202212206284
M3 - статья
VL - 122
SP - 84
EP - 90
JO - ЖУРНАЛ НЕВРОЛОГИИ И ПСИХИАТРИИ ИМ. C.C. КОРСАКОВА
JF - ЖУРНАЛ НЕВРОЛОГИИ И ПСИХИАТРИИ ИМ. C.C. КОРСАКОВА
SN - 1997-7298
IS - 6 Vyp 2
ER -
ID: 97145183