ЭПИГЕНЕТИЧЕСКИЕ МОДИФИКАЦИИ ПРИ ВЫПОЛНЕНИИ ФИЗИЧЕСКИХ НАГРУЗОК. / Golberg, N. D.; Astratenkova, I. V.; Akhmetov, I. I.; Rogozkin, V. A.
In: ТЕОРИЯ И ПРАКТИКА ФИЗИЧЕСКОЙ КУЛЬТУРЫ, No. 2, 01.02.2018, p. 51-53.Research output: Contribution to journal › Article › peer-review
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TY - JOUR
T1 - ЭПИГЕНЕТИЧЕСКИЕ МОДИФИКАЦИИ ПРИ ВЫПОЛНЕНИИ ФИЗИЧЕСКИХ НАГРУЗОК
AU - Golberg, N. D.
AU - Astratenkova, I. V.
AU - Akhmetov, I. I.
AU - Rogozkin, V. A.
PY - 2018/2/1
Y1 - 2018/2/1
N2 - Mapping on the human genome and genome of other organisms revealed not only the DNA organization principles, but also showed the regulation complexity of the structural and metabolic genes expression. It turned out that external influences such as nutrition, stress, physical activity and other external stimuli change genes expression and control it through a complex set of regulatory mechanisms. A complex set of molecular mechanisms, including genetic and epigenetic factors, is involved in the regulation of skeletal muscle metabolism. Epigenetic regulation of gene expression in human skeletal muscles is carried out at three levels: DNA methylation, histone modification and mRNA-microRNA interaction. The article considers the possible mechanisms of epigenetic regulation of intracellular metabolism of skeletal muscles during single and systematic exercises.
AB - Mapping on the human genome and genome of other organisms revealed not only the DNA organization principles, but also showed the regulation complexity of the structural and metabolic genes expression. It turned out that external influences such as nutrition, stress, physical activity and other external stimuli change genes expression and control it through a complex set of regulatory mechanisms. A complex set of molecular mechanisms, including genetic and epigenetic factors, is involved in the regulation of skeletal muscle metabolism. Epigenetic regulation of gene expression in human skeletal muscles is carried out at three levels: DNA methylation, histone modification and mRNA-microRNA interaction. The article considers the possible mechanisms of epigenetic regulation of intracellular metabolism of skeletal muscles during single and systematic exercises.
KW - DNA methylation
KW - Epigenetics
KW - Exercise
KW - MicroRNA
KW - Modification of histones
UR - http://www.scopus.com/inward/record.url?scp=85044511763&partnerID=8YFLogxK
M3 - статья
AN - SCOPUS:85044511763
SP - 51
EP - 53
JO - THEORY AND PRACTICE OF PHYSICAL CULTURE
JF - THEORY AND PRACTICE OF PHYSICAL CULTURE
SN - 2409-4234
IS - 2
ER -
ID: 36518845