The venous bed of the epidural space was studied in 32 preparations of the vertebral column of adults of the II period of adulthood using injection and corrosion techniques, stereoepiduroscopy and Pirogov sections. The topographic anatomy of the internal vertebral venous plexus and the features of its structure in different parts of the spinal canal are presented. The main, mixed, and reticular forms of the studied plexus are distinguished. Data on changes in the cross-sectional area of the internal vertebral venous plexus in the cranio-caudal direction are presented. The structural and functional characteristics of the venous plexus, its relationship with connective tissue structures of the epidural space and their practical significance are considered. To prevent possible complications of various medical procedures, data on avascular zones of the epidural space are presented. Based on the anatomical features of the topography of the arcuate anastomoses of the posterior longitudinal veins of the internal vertebral plexus, zones have been identified in different departments in which manipulations can be carried out with a greater degree of caution: the dangerous zone is level C_I-VII, Th_I-XII; relative safety zone - level L_I-V; safe - zone S_I-IV