This study indicates a mitochondrial-reticular network, functionally integrated into the processes that provide energy to all systems of the organism as open, dynamic, self-regulatory organization involved in the energy homeostasis of the cell under the control of AMP-activated protein kinase as the main energy indicator. The mitochondrial-reticular network is regulated by at least three multidirectional energy vectors - mitochondrial fission and fusion, and mitochondrial apoptosis mechanisms. A kinetic mathematical model of mitochondrial-reticular network function is proposed. A search for effective strategies for the functioning of mitochondrial-reticular network is resolved into constrained optimization through the use of the Lagrange multiplier.