Результаты исследований: Научные публикации в периодических изданиях › Обзорная статья › Рецензирование
Understanding zebrafish aggressive behavior. / Zabegalov, Konstantin N.; Kolesnikova, Tatiana O.; Khatsko, Sergey L.; Volgin, Andrey D.; Yakovlev, Oleg A.; Amstislavskaya, Tamara G.; Friend, Ashton J.; Bao, Wandong; Alekseeva, Polina A.; Lakstygal, Anton M.; Meshalkina, Darya A.; Demin, Konstantin A.; de Abreu, Murilo S.; Rosemberg, Denis B.; Kalueff, Allan V.
в: Behavioural Processes, Том 158, 01.01.2019, стр. 200-210.Результаты исследований: Научные публикации в периодических изданиях › Обзорная статья › Рецензирование
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TY - JOUR
T1 - Understanding zebrafish aggressive behavior
AU - Zabegalov, Konstantin N.
AU - Kolesnikova, Tatiana O.
AU - Khatsko, Sergey L.
AU - Volgin, Andrey D.
AU - Yakovlev, Oleg A.
AU - Amstislavskaya, Tamara G.
AU - Friend, Ashton J.
AU - Bao, Wandong
AU - Alekseeva, Polina A.
AU - Lakstygal, Anton M.
AU - Meshalkina, Darya A.
AU - Demin, Konstantin A.
AU - de Abreu, Murilo S.
AU - Rosemberg, Denis B.
AU - Kalueff, Allan V.
PY - 2019/1/1
Y1 - 2019/1/1
N2 - Aggression is a common agonistic behavior affecting social life and well-being of humans and animals. However, the underlying mechanisms of aggression remain poorly understood. For decades, studies of aggression have mostly focused on laboratory rodents. The growing importance of evolutionarily relevant, cross-species disease modeling necessitates novel model organisms to study aggression and its pathobiology. The zebrafish (Danio rerio) is rapidly becoming a new experimental model organism in neurobehavioral research. Zebrafish demonstrate high genetic and physiological homology with mammals, fully sequenced genome, ease of husbandry and testing, as well as rich, robust behavioral repertoire. As zebrafish present overt aggressive behaviors, here we focus on their behavioral models and discuss their utility in probing aggression neurobiology and its genetic, pharmacological and environmental modulation. We argue that zebrafish-based models represent an excellent translational tool to understand aggressive behaviors and related pathobiological brain mechanisms.
AB - Aggression is a common agonistic behavior affecting social life and well-being of humans and animals. However, the underlying mechanisms of aggression remain poorly understood. For decades, studies of aggression have mostly focused on laboratory rodents. The growing importance of evolutionarily relevant, cross-species disease modeling necessitates novel model organisms to study aggression and its pathobiology. The zebrafish (Danio rerio) is rapidly becoming a new experimental model organism in neurobehavioral research. Zebrafish demonstrate high genetic and physiological homology with mammals, fully sequenced genome, ease of husbandry and testing, as well as rich, robust behavioral repertoire. As zebrafish present overt aggressive behaviors, here we focus on their behavioral models and discuss their utility in probing aggression neurobiology and its genetic, pharmacological and environmental modulation. We argue that zebrafish-based models represent an excellent translational tool to understand aggressive behaviors and related pathobiological brain mechanisms.
KW - Aggression
KW - Environmental modulation
KW - Experimental models
KW - Pharmacology of aggression
KW - Zebrafish
KW - Animals
KW - Zebrafish/physiology
KW - Behavior, Animal/physiology
KW - Brain/physiology
KW - Aggression/physiology
UR - http://www.scopus.com/inward/record.url?scp=85058388059&partnerID=8YFLogxK
UR - http://www.mendeley.com/research/understanding-zebrafish-aggressive-behavior
U2 - 10.1016/j.beproc.2018.11.010
DO - 10.1016/j.beproc.2018.11.010
M3 - Review article
C2 - 30468887
AN - SCOPUS:85058388059
VL - 158
SP - 200
EP - 210
JO - Behavioural Processes
JF - Behavioural Processes
SN - 0376-6357
ER -
ID: 47610406