THE RELATIONSHIP BETWEEN ELEVATED LIPOPROTEIN(A) LEVELS AND ANTIATHEROGENIC TOLL-LIKE RECEPTOR GENES POLYMORPHISM IN FAMILIAL HYPERCHOLESTEROLEMIA

M. Muzalevskaya, O. Afanasieva, N. Razgildina, S. A. Urazgildeeva, V. V. Miroshnikova, V. S. Gurevich

Результат исследований: Научные публикации в периодических изданияхтезисырецензирование

Аннотация

It was recently demonstrated that G allele of the rs4986790 polymorphism (Asp299Gly) of TLR4 Gene (AG genotype) has been associated with decreased development of atherosclerosis. The aim of the study was to analyze the relationships between polymorphism of TLR4 Gene and lipid disorders in patients with familial hypercholesterolemia (FH) since it is known that a part of FH patients do not manifest cardiovascular event regardless elevated low density lipoprotein cholesterol (LDL-C) levels.
Язык оригиналаАнглийский
Страницы (с-по)E116-E116
Число страниц1
ЖурналAtherosclerosis
Том331
DOI
СостояниеОпубликовано - авг 2021

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