The lack of cyclin-dependent phosphoprotein kinase Pho85p leads to defects in mitochondrial nucleoid transmission in yeast Saccharomyces cerevisiae

E. V. Sambuk, A. I. Fizikova, K. V. Zakharova, A. M. Smirnov, M. V. Padkina

Результат исследований: Научные публикации в периодических изданияхстатья

4 Цитирования (Scopus)

Выдержка

Cyclin-dependent phosphoprotein kinases (CDK) play essential role in the regulation of the progression through different phases of the cell cycle, being also involved in metabolic regulation and in actin cytoskeleton organization. The Saccharomyces cerevisiae CDK Pho85p is associated with 10 different cyclins and phosphorylates different substrates, among these transcription factors Pho4p and Gcn4p, and a protein involved in actin polymerization being a homologue of amphiphysin 1 of mammalian Rvs167p. It is known that mutations in the PHO85 gene have a multiple pleotropic effects, one of these effects being a rapid accumulation of mitochondrial [rho-] mutations observed on the background of gene PHO85 inactivation. In this study it was shown that the appearance of [rho-] clones is a result of some defects in mitochondrial nucleoid transmission from mother to bud cells.

Язык оригиналаанглийский
Страницы (с-по)917-924
Число страниц8
ЖурналTsitologiia.
Том47
Номер выпуска10
СостояниеОпубликовано - 1 дек 2005

Отпечаток

Cyclin-Dependent Kinases
Phosphoproteins
Saccharomyces cerevisiae
Yeasts
Mutation
Cyclins
Gene Silencing
Actin Cytoskeleton
Polymerization
Actins
Cell Cycle
Transcription Factors
Clone Cells
Genes
Proteins
amphiphysin

Предметные области Scopus

  • Медицина (все)

Цитировать

@article{88281589978f4c0eaa8069138b37d185,
title = "The lack of cyclin-dependent phosphoprotein kinase Pho85p leads to defects in mitochondrial nucleoid transmission in yeast Saccharomyces cerevisiae",
abstract = "Cyclin-dependent phosphoprotein kinases (CDK) play essential role in the regulation of the progression through different phases of the cell cycle, being also involved in metabolic regulation and in actin cytoskeleton organization. The Saccharomyces cerevisiae CDK Pho85p is associated with 10 different cyclins and phosphorylates different substrates, among these transcription factors Pho4p and Gcn4p, and a protein involved in actin polymerization being a homologue of amphiphysin 1 of mammalian Rvs167p. It is known that mutations in the PHO85 gene have a multiple pleotropic effects, one of these effects being a rapid accumulation of mitochondrial [rho-] mutations observed on the background of gene PHO85 inactivation. In this study it was shown that the appearance of [rho-] clones is a result of some defects in mitochondrial nucleoid transmission from mother to bud cells.",
author = "Sambuk, {E. V.} and Fizikova, {A. I.} and Zakharova, {K. V.} and Smirnov, {A. M.} and Padkina, {M. V.}",
year = "2005",
month = "12",
day = "1",
language = "English",
volume = "47",
pages = "917--924",
journal = "Цитология",
issn = "0041-3771",
publisher = "МАИК {"}Наука/Интерпериодика{"}",
number = "10",

}

The lack of cyclin-dependent phosphoprotein kinase Pho85p leads to defects in mitochondrial nucleoid transmission in yeast Saccharomyces cerevisiae. / Sambuk, E. V.; Fizikova, A. I.; Zakharova, K. V.; Smirnov, A. M.; Padkina, M. V.

В: Tsitologiia., Том 47, № 10, 01.12.2005, стр. 917-924.

Результат исследований: Научные публикации в периодических изданияхстатья

TY - JOUR

T1 - The lack of cyclin-dependent phosphoprotein kinase Pho85p leads to defects in mitochondrial nucleoid transmission in yeast Saccharomyces cerevisiae

AU - Sambuk, E. V.

AU - Fizikova, A. I.

AU - Zakharova, K. V.

AU - Smirnov, A. M.

AU - Padkina, M. V.

PY - 2005/12/1

Y1 - 2005/12/1

N2 - Cyclin-dependent phosphoprotein kinases (CDK) play essential role in the regulation of the progression through different phases of the cell cycle, being also involved in metabolic regulation and in actin cytoskeleton organization. The Saccharomyces cerevisiae CDK Pho85p is associated with 10 different cyclins and phosphorylates different substrates, among these transcription factors Pho4p and Gcn4p, and a protein involved in actin polymerization being a homologue of amphiphysin 1 of mammalian Rvs167p. It is known that mutations in the PHO85 gene have a multiple pleotropic effects, one of these effects being a rapid accumulation of mitochondrial [rho-] mutations observed on the background of gene PHO85 inactivation. In this study it was shown that the appearance of [rho-] clones is a result of some defects in mitochondrial nucleoid transmission from mother to bud cells.

AB - Cyclin-dependent phosphoprotein kinases (CDK) play essential role in the regulation of the progression through different phases of the cell cycle, being also involved in metabolic regulation and in actin cytoskeleton organization. The Saccharomyces cerevisiae CDK Pho85p is associated with 10 different cyclins and phosphorylates different substrates, among these transcription factors Pho4p and Gcn4p, and a protein involved in actin polymerization being a homologue of amphiphysin 1 of mammalian Rvs167p. It is known that mutations in the PHO85 gene have a multiple pleotropic effects, one of these effects being a rapid accumulation of mitochondrial [rho-] mutations observed on the background of gene PHO85 inactivation. In this study it was shown that the appearance of [rho-] clones is a result of some defects in mitochondrial nucleoid transmission from mother to bud cells.

UR - http://www.scopus.com/inward/record.url?scp=33745113250&partnerID=8YFLogxK

M3 - Article

C2 - 16711391

AN - SCOPUS:33745113250

VL - 47

SP - 917

EP - 924

JO - Цитология

JF - Цитология

SN - 0041-3771

IS - 10

ER -