The development of muscle fatigue suppresses auditory sensory gating (P50) during sustained contraction

Результат исследований: Научные публикации в периодических изданияхстатья

4 Цитирования (Scopus)
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Our aim was to study the influence of fatigue development on sensory gating during a muscle load. The fatiguing task was sustained contraction of a handgrip dynamometer with 7 and 30% maximum voluntary contraction (MVC). The suppression of P50, an auditory event-related potential, was used as the sensory gating index in the pairedclick paradigm with a 500 ms interstimulus interval; the difference between the P50 amplitudes of the first and the second stimuli of the pair was used as the sensory gating index. We found that the 30% MVC fatigue development strongly decreased sensory gating, sometimes totally suppressing it. We concluded that central fatigue impaired motor performance and strongly suppressed inhibitory processes, as shown by the decreased P50 amplitude to the second stimulus. Therefore, muscle central fatigue influences sensory gating, similar to schizophrenia spectrum disorders.
Язык оригиналаанглийский
Страницы (с-по)44
Число страниц6
ЖурналFrontiers in Systems Neuroscience
Том10
Номер выпуска44
DOI
СостояниеОпубликовано - 20 мая 2016

Отпечаток

Sensory Gating
Muscle Fatigue
Fatigue
Evoked Potentials
Schizophrenia
Muscles

Предметные области Scopus

  • Нейробиология (все)

Цитировать

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title = "The development of muscle fatigue suppresses auditory sensory gating (P50) during sustained contraction",
abstract = "Our aim was to study the influence of fatigue development on sensory gating during a muscle load. The fatiguing task was sustained contraction of a handgrip dynamometer with 7 and 30{\%} maximum voluntary contraction (MVC). The suppression of P50, an auditory event-related potential, was used as the sensory gating index in the pairedclick paradigm with a 500 ms interstimulus interval; the difference between the P50 amplitudes of the first and the second stimuli of the pair was used as the sensory gating index. We found that the 30{\%} MVC fatigue development strongly decreased sensory gating, sometimes totally suppressing it. We concluded that central fatigue impaired motor performance and strongly suppressed inhibitory processes, as shown by the decreased P50 amplitude to the second stimulus. Therefore, muscle central fatigue influences sensory gating, similar to schizophrenia spectrum disorders.",
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author = "Aleksandrov, {Aleksander A.} and Dmitrieva, {Elena S.} and Stankevich, {Ludmila N.} and Knyazeva, {Veronika M.} and Shestakova, {Anna N.}",
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The development of muscle fatigue suppresses auditory sensory gating (P50) during sustained contraction. / Aleksandrov, Aleksander A.; Dmitrieva, Elena S.; Stankevich, Ludmila N.; Knyazeva, Veronika M.; Shestakova, Anna N.

В: Frontiers in Systems Neuroscience, Том 10, № 44, 20.05.2016, стр. 44.

Результат исследований: Научные публикации в периодических изданияхстатья

TY - JOUR

T1 - The development of muscle fatigue suppresses auditory sensory gating (P50) during sustained contraction

AU - Aleksandrov, Aleksander A.

AU - Dmitrieva, Elena S.

AU - Stankevich, Ludmila N.

AU - Knyazeva, Veronika M.

AU - Shestakova, Anna N.

PY - 2016/5/20

Y1 - 2016/5/20

N2 - Our aim was to study the influence of fatigue development on sensory gating during a muscle load. The fatiguing task was sustained contraction of a handgrip dynamometer with 7 and 30% maximum voluntary contraction (MVC). The suppression of P50, an auditory event-related potential, was used as the sensory gating index in the pairedclick paradigm with a 500 ms interstimulus interval; the difference between the P50 amplitudes of the first and the second stimuli of the pair was used as the sensory gating index. We found that the 30% MVC fatigue development strongly decreased sensory gating, sometimes totally suppressing it. We concluded that central fatigue impaired motor performance and strongly suppressed inhibitory processes, as shown by the decreased P50 amplitude to the second stimulus. Therefore, muscle central fatigue influences sensory gating, similar to schizophrenia spectrum disorders.

AB - Our aim was to study the influence of fatigue development on sensory gating during a muscle load. The fatiguing task was sustained contraction of a handgrip dynamometer with 7 and 30% maximum voluntary contraction (MVC). The suppression of P50, an auditory event-related potential, was used as the sensory gating index in the pairedclick paradigm with a 500 ms interstimulus interval; the difference between the P50 amplitudes of the first and the second stimuli of the pair was used as the sensory gating index. We found that the 30% MVC fatigue development strongly decreased sensory gating, sometimes totally suppressing it. We concluded that central fatigue impaired motor performance and strongly suppressed inhibitory processes, as shown by the decreased P50 amplitude to the second stimulus. Therefore, muscle central fatigue influences sensory gating, similar to schizophrenia spectrum disorders.

KW - sensory gating

KW - auditory P50 suppression

KW - schizophrenia

KW - central muscle fatigue

KW - event-relatedpotentials

KW - mismatch negativity

KW - attention

KW - preattentive auditory information processing

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