The 1,3-dipolar cycloaddition of adamantine-derived nitrones with maleimides

Alexander P. Molchanov, Valentina M. Lukina, Mariia M. Efremova, Anna A. Muryleva, Alexander V. Slita, Vladimir V. Zarubaev

Результат исследований: Научные публикации в периодических изданияхстатья

Аннотация

Adamantane-derived aldo- and ketonitrones react with maleimides giving corresponding isoxazolidines. In the case of aldonitrones reactions proceed giving the diastereomeric mixtures. The ratio of isomers is changing during the reaction process due to the reversibility of the cycloaddition reaction. The cytotoxic and virus-inhibiting activity against influenza virus was investigated for selected adducts.

Язык оригиналаанглийский
ЖурналSynthetic Communications
DOI
СостояниеЭлектронная публикация перед печатью - 18 мар 2020

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Предметные области Scopus

  • Органическая химия

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