Spongosine production by a vibrio harveyi strain associated with the sponge tectitethya crypta

M.J. Bertin, S.L. Schwartz, J. Lee, A. Korobeynikov, P.C. Dorrestein, L. Gerwick, W.H. Gerwick

Результат исследований: Научные публикации в периодических изданияхстатья

17 Цитирования (Scopus)

Выдержка

© 2015 The American Chemical Society and American Society of Pharmacognosy. Spongosine (1), deoxyspongosine (2), spongothymidine (Ara T) (3), and spongouridine (Ara U) were isolated from the Caribbean sponge Tectitethya crypta and given the general name pongonucleosides. Spongosine, a methoxyadenosine derivative, has demonstrated a diverse bioactivity profile including anti-inflammatory activity and analgesic and vasodilation properties. Investigations into unusual nucleoside production by T. crypta-associated microorganisms using mass spectrometric techniques have identified a spongosine-producing strain of Vibrio harveyi and several structurally related compounds from multiple strains.
Язык оригиналаанглийский
Страницы (с-по)493-499
ЖурналJournal of Natural Products
Том78
Номер выпуска3
DOI
СостояниеОпубликовано - 2015

Отпечаток

Arabinofuranosyluracil
Vibrio
Porifera
Non-Steroidal Anti-Inflammatory Agents
Bioactivity
Nucleosides
Vasodilation
Microorganisms
Names
Analgesics
Anti-Inflammatory Agents
Derivatives
ara-T

Цитировать

Bertin, M. J., Schwartz, S. L., Lee, J., Korobeynikov, A., Dorrestein, P. C., Gerwick, L., & Gerwick, W. H. (2015). Spongosine production by a vibrio harveyi strain associated with the sponge tectitethya crypta. Journal of Natural Products, 78(3), 493-499. https://doi.org/10.1021/np5009762
Bertin, M.J. ; Schwartz, S.L. ; Lee, J. ; Korobeynikov, A. ; Dorrestein, P.C. ; Gerwick, L. ; Gerwick, W.H. / Spongosine production by a vibrio harveyi strain associated with the sponge tectitethya crypta. В: Journal of Natural Products. 2015 ; Том 78, № 3. стр. 493-499.
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Bertin, MJ, Schwartz, SL, Lee, J, Korobeynikov, A, Dorrestein, PC, Gerwick, L & Gerwick, WH 2015, 'Spongosine production by a vibrio harveyi strain associated with the sponge tectitethya crypta', Journal of Natural Products, том. 78, № 3, стр. 493-499. https://doi.org/10.1021/np5009762

Spongosine production by a vibrio harveyi strain associated with the sponge tectitethya crypta. / Bertin, M.J.; Schwartz, S.L.; Lee, J.; Korobeynikov, A.; Dorrestein, P.C.; Gerwick, L.; Gerwick, W.H.

В: Journal of Natural Products, Том 78, № 3, 2015, стр. 493-499.

Результат исследований: Научные публикации в периодических изданияхстатья

TY - JOUR

T1 - Spongosine production by a vibrio harveyi strain associated with the sponge tectitethya crypta

AU - Bertin, M.J.

AU - Schwartz, S.L.

AU - Lee, J.

AU - Korobeynikov, A.

AU - Dorrestein, P.C.

AU - Gerwick, L.

AU - Gerwick, W.H.

PY - 2015

Y1 - 2015

N2 - © 2015 The American Chemical Society and American Society of Pharmacognosy. Spongosine (1), deoxyspongosine (2), spongothymidine (Ara T) (3), and spongouridine (Ara U) were isolated from the Caribbean sponge Tectitethya crypta and given the general name pongonucleosides. Spongosine, a methoxyadenosine derivative, has demonstrated a diverse bioactivity profile including anti-inflammatory activity and analgesic and vasodilation properties. Investigations into unusual nucleoside production by T. crypta-associated microorganisms using mass spectrometric techniques have identified a spongosine-producing strain of Vibrio harveyi and several structurally related compounds from multiple strains.

AB - © 2015 The American Chemical Society and American Society of Pharmacognosy. Spongosine (1), deoxyspongosine (2), spongothymidine (Ara T) (3), and spongouridine (Ara U) were isolated from the Caribbean sponge Tectitethya crypta and given the general name pongonucleosides. Spongosine, a methoxyadenosine derivative, has demonstrated a diverse bioactivity profile including anti-inflammatory activity and analgesic and vasodilation properties. Investigations into unusual nucleoside production by T. crypta-associated microorganisms using mass spectrometric techniques have identified a spongosine-producing strain of Vibrio harveyi and several structurally related compounds from multiple strains.

U2 - 10.1021/np5009762

DO - 10.1021/np5009762

M3 - Article

VL - 78

SP - 493

EP - 499

JO - Journal of Natural Products

JF - Journal of Natural Products

SN - 0163-3864

IS - 3

ER -