Sarcoidosis as an Autoimmune Disease

Anna A. Starshinova, Anna M. Malkova, Natalia Y. Basantsova, Yulia S. Zinchenko, Igor V. Kudryavtsev, Gennadiy A. Ershov, Lidia A. Soprun, Vera A. Mayevskaya, Leonid P. Churilov, Piotr K. Yablonskiy Yablonskiy

Результат исследований: Научные публикации в периодических изданияхстатья

Выдержка

Despite the large number of performed studies, the etiology and pathogenesis of sarcoidosis still remain unknown. Most researchers allude to the possible autoimmune or immune-mediated genesis of the disease. This review attempts an integral analysis of currently available information suggesting an autoimmune genesis of sarcoidosis and is divided into four categories: the evaluation of clinical signs described both in patients with sarcoidosis and “classic” autoimmune diseases, the role of triggering factors in the development of sarcoidosis, the presence of immunogenic susceptibility in the development of the disease, and the analysis of cellular and humoral immune responses in sarcoidosis. Studying the etiology and pathogenesis of sarcoidosis will improve diagnostic procedures as well as the prognosis and patients' quality of life.

Язык оригиналаанглийский
Номер статьи2933
ЖурналFrontiers in Immunology
Том10
DOI
СостояниеОпубликовано - 8 янв 2020

Отпечаток

Sarcoidosis
Autoimmune Diseases
Humoral Immunity
Cellular Immunity
Quality of Life
Research Personnel

Предметные области Scopus

  • Иммунология и аллергии
  • Иммунология

Цитировать

Starshinova, Anna A. ; Malkova, Anna M. ; Basantsova, Natalia Y. ; Zinchenko, Yulia S. ; Kudryavtsev, Igor V. ; Ershov, Gennadiy A. ; Soprun, Lidia A. ; Mayevskaya, Vera A. ; Churilov, Leonid P. ; Yablonskiy, Piotr K. Yablonskiy. / Sarcoidosis as an Autoimmune Disease. В: Frontiers in Immunology. 2020 ; Том 10.
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abstract = "Despite the large number of performed studies, the etiology and pathogenesis of sarcoidosis still remain unknown. Most researchers allude to the possible autoimmune or immune-mediated genesis of the disease. This review attempts an integral analysis of currently available information suggesting an autoimmune genesis of sarcoidosis and is divided into four categories: the evaluation of clinical signs described both in patients with sarcoidosis and “classic” autoimmune diseases, the role of triggering factors in the development of sarcoidosis, the presence of immunogenic susceptibility in the development of the disease, and the analysis of cellular and humoral immune responses in sarcoidosis. Studying the etiology and pathogenesis of sarcoidosis will improve diagnostic procedures as well as the prognosis and patients' quality of life.",
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Sarcoidosis as an Autoimmune Disease. / Starshinova, Anna A.; Malkova, Anna M. ; Basantsova, Natalia Y. ; Zinchenko, Yulia S. ; Kudryavtsev, Igor V. ; Ershov, Gennadiy A. ; Soprun, Lidia A. ; Mayevskaya, Vera A. ; Churilov, Leonid P. ; Yablonskiy, Piotr K. Yablonskiy.

В: Frontiers in Immunology, Том 10, 2933, 08.01.2020.

Результат исследований: Научные публикации в периодических изданияхстатья

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AU - Zinchenko, Yulia S.

AU - Kudryavtsev, Igor V.

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AU - Soprun, Lidia A.

AU - Mayevskaya, Vera A.

AU - Churilov, Leonid P.

AU - Yablonskiy, Piotr K. Yablonskiy

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