Rediae of echinostomatid and heterophyid trematodes suppress phagocytosis of haemocytes in Littorina littorea (Gastropoda Prosobranchia)

Nadya V. Iakovleva, Tania G. Shaposhnikova, Alexander M. Gorbushin

Результат исследований: Научные публикации в периодических изданияхстатья

22 Цитирования (Scopus)

Выдержка

A modulation of the phagocytic activity of hemocytes from the common periwinkle Littorina littorea by secretory-excretory products (SEP) released by trematode rediae during axenic in vitro cultivation was studied. The SEP released by the parasites Himasthla elongata (Echinostomatidae) and Cryptocotyle lingua (Heterophyidae) were found to inhibit the phagocytosis of zymozan particles by periwinkle hemocytes. The specificity of SEP effects was assessed: SEP of Himasthla militaris and Cryptocotyle concavum, two trematodes belonging to the same genera but infecting another closely related prosobranch snail Hydrobia ulvae, were also shown to be able to suppress L. littorea hemocytes phagocytic activity. However, no decrease in phagocytosis rate was observed when SEP of H. elongata and C. lingua were applied to monolayers of hemocytes from the bivalve mollusc Mytilus edulis. SEP from H. elongata was fractionated; only those fractions containing proteins of molecular weight more than 50 kDa were shown to possess inhibitory activity. Different H. elongata SEP concentrations were tested in for their ability to suppress phagocytosis by L. littorea hemocytes. Even very low SEP concentrations were shown to retain their ability to decrease phagocytosis rate, the inhibitory effect being dose-dependent. Hemocytes derived from snails naturally infected with H. elongata were also found to have lower phagocytic ability as compared to healthy individuals.

Язык оригиналаанглийский
Страницы (с-по)24-29
Число страниц6
ЖурналExperimental Parasitology
Том113
Номер выпуска1
DOI
СостояниеОпубликовано - 1 мая 2006

Отпечаток

Hemocytes
Gastropoda
Phagocytosis
Vinca
Trematoda
Snails
Echinostomatidae
Heterophyidae
Mytilus edulis
Mollusca
Bivalvia
Parasites
Molecular Weight
Proteins

Предметные области Scopus

  • Паразитология
  • Иммунология

Цитировать

@article{ace4792c6e98459f91d11e64ef498783,
title = "Rediae of echinostomatid and heterophyid trematodes suppress phagocytosis of haemocytes in Littorina littorea (Gastropoda Prosobranchia)",
abstract = "A modulation of the phagocytic activity of hemocytes from the common periwinkle Littorina littorea by secretory-excretory products (SEP) released by trematode rediae during axenic in vitro cultivation was studied. The SEP released by the parasites Himasthla elongata (Echinostomatidae) and Cryptocotyle lingua (Heterophyidae) were found to inhibit the phagocytosis of zymozan particles by periwinkle hemocytes. The specificity of SEP effects was assessed: SEP of Himasthla militaris and Cryptocotyle concavum, two trematodes belonging to the same genera but infecting another closely related prosobranch snail Hydrobia ulvae, were also shown to be able to suppress L. littorea hemocytes phagocytic activity. However, no decrease in phagocytosis rate was observed when SEP of H. elongata and C. lingua were applied to monolayers of hemocytes from the bivalve mollusc Mytilus edulis. SEP from H. elongata was fractionated; only those fractions containing proteins of molecular weight more than 50 kDa were shown to possess inhibitory activity. Different H. elongata SEP concentrations were tested in for their ability to suppress phagocytosis by L. littorea hemocytes. Even very low SEP concentrations were shown to retain their ability to decrease phagocytosis rate, the inhibitory effect being dose-dependent. Hemocytes derived from snails naturally infected with H. elongata were also found to have lower phagocytic ability as compared to healthy individuals.",
keywords = "Cryptocotyle concavum, Cryptocotyle lingua, Echinostomatidae, filtered sea water, FSW, Haemocytes, Heterophyidae, Himasthla elongata, Himasthla militaris, Hydrobia ulvae, Innate immunity, Littorina littorea, Mollusca, Mytilus edulis, Phagocytosis, phagocytosis index, PI, secretory-excretory products, SEP, Trematoda",
author = "Iakovleva, {Nadya V.} and Shaposhnikova, {Tania G.} and Gorbushin, {Alexander M.}",
year = "2006",
month = "5",
day = "1",
doi = "10.1016/j.exppara.2005.12.002",
language = "English",
volume = "113",
pages = "24--29",
journal = "Experimental Parasitology",
issn = "0014-4894",
publisher = "Elsevier",
number = "1",

}

Rediae of echinostomatid and heterophyid trematodes suppress phagocytosis of haemocytes in Littorina littorea (Gastropoda Prosobranchia). / Iakovleva, Nadya V.; Shaposhnikova, Tania G.; Gorbushin, Alexander M.

В: Experimental Parasitology, Том 113, № 1, 01.05.2006, стр. 24-29.

Результат исследований: Научные публикации в периодических изданияхстатья

TY - JOUR

T1 - Rediae of echinostomatid and heterophyid trematodes suppress phagocytosis of haemocytes in Littorina littorea (Gastropoda Prosobranchia)

AU - Iakovleva, Nadya V.

AU - Shaposhnikova, Tania G.

AU - Gorbushin, Alexander M.

PY - 2006/5/1

Y1 - 2006/5/1

N2 - A modulation of the phagocytic activity of hemocytes from the common periwinkle Littorina littorea by secretory-excretory products (SEP) released by trematode rediae during axenic in vitro cultivation was studied. The SEP released by the parasites Himasthla elongata (Echinostomatidae) and Cryptocotyle lingua (Heterophyidae) were found to inhibit the phagocytosis of zymozan particles by periwinkle hemocytes. The specificity of SEP effects was assessed: SEP of Himasthla militaris and Cryptocotyle concavum, two trematodes belonging to the same genera but infecting another closely related prosobranch snail Hydrobia ulvae, were also shown to be able to suppress L. littorea hemocytes phagocytic activity. However, no decrease in phagocytosis rate was observed when SEP of H. elongata and C. lingua were applied to monolayers of hemocytes from the bivalve mollusc Mytilus edulis. SEP from H. elongata was fractionated; only those fractions containing proteins of molecular weight more than 50 kDa were shown to possess inhibitory activity. Different H. elongata SEP concentrations were tested in for their ability to suppress phagocytosis by L. littorea hemocytes. Even very low SEP concentrations were shown to retain their ability to decrease phagocytosis rate, the inhibitory effect being dose-dependent. Hemocytes derived from snails naturally infected with H. elongata were also found to have lower phagocytic ability as compared to healthy individuals.

AB - A modulation of the phagocytic activity of hemocytes from the common periwinkle Littorina littorea by secretory-excretory products (SEP) released by trematode rediae during axenic in vitro cultivation was studied. The SEP released by the parasites Himasthla elongata (Echinostomatidae) and Cryptocotyle lingua (Heterophyidae) were found to inhibit the phagocytosis of zymozan particles by periwinkle hemocytes. The specificity of SEP effects was assessed: SEP of Himasthla militaris and Cryptocotyle concavum, two trematodes belonging to the same genera but infecting another closely related prosobranch snail Hydrobia ulvae, were also shown to be able to suppress L. littorea hemocytes phagocytic activity. However, no decrease in phagocytosis rate was observed when SEP of H. elongata and C. lingua were applied to monolayers of hemocytes from the bivalve mollusc Mytilus edulis. SEP from H. elongata was fractionated; only those fractions containing proteins of molecular weight more than 50 kDa were shown to possess inhibitory activity. Different H. elongata SEP concentrations were tested in for their ability to suppress phagocytosis by L. littorea hemocytes. Even very low SEP concentrations were shown to retain their ability to decrease phagocytosis rate, the inhibitory effect being dose-dependent. Hemocytes derived from snails naturally infected with H. elongata were also found to have lower phagocytic ability as compared to healthy individuals.

KW - Cryptocotyle concavum

KW - Cryptocotyle lingua

KW - Echinostomatidae

KW - filtered sea water

KW - FSW

KW - Haemocytes

KW - Heterophyidae

KW - Himasthla elongata

KW - Himasthla militaris

KW - Hydrobia ulvae

KW - Innate immunity

KW - Littorina littorea

KW - Mollusca

KW - Mytilus edulis

KW - Phagocytosis

KW - phagocytosis index

KW - PI

KW - secretory-excretory products

KW - SEP

KW - Trematoda

UR - http://www.scopus.com/inward/record.url?scp=33646517491&partnerID=8YFLogxK

U2 - 10.1016/j.exppara.2005.12.002

DO - 10.1016/j.exppara.2005.12.002

M3 - Article

C2 - 16438967

AN - SCOPUS:33646517491

VL - 113

SP - 24

EP - 29

JO - Experimental Parasitology

JF - Experimental Parasitology

SN - 0014-4894

IS - 1

ER -