Aim. To study psychic, cognitive status and life quality of petients underwent coronary bypass grafting (CABG). Material and methods. Totally 81 patient with CHD studied (80% men, 20% women) with the age 56,3±1 y. o., underwent planned CABG. On 7–8th day after CABG the 6-minute walk test (WT) was done and the Hospital anxiety-depression score used, Hamilton anxiety-depression score, Spielberger anxiety score and other methods to assess asthenia and cognitive status (MMSE, MoCA). Life Quality (LQ) assessed with 10-points visual-analogue scale; coping behavioural strategies studied. Results. Values by WT were 415±130 m, LQ — 6±0,3 points. In 35% patients there was lowering of cognitive functioning. In 20% there were affective disorders and the negative correlation of WT with anxiety (r= –0,3; p<0,01), affective disorders with LQ (r= –0,53; p<0,05). Anxiety was comorbid to depression (r=0,91; p<0,05). Moderate and prominent asthenia registered in 36% and 18% of patients, asthenia was linked with affective (r=0,96; <0,02) and cognitive (r=0,97; <0,001) disorders. 46% patients used non-constructive and relatively constructive coping strategies. Conclusion. On 7–8th days after CABG in 35% patients there is lowering of cognitive functioning and not less than 20% show signs of affective disorders, that impacts LQ of patients and tolerability of physical exertion. The anxiety and depression revealed were associated not only with each other but with asthenisation of patients to. Cognitive disorders and emotional dyscomfort, experiencing by patients, may affect adaptation leading to non-constructive coping strategies. The found specifics of psychic and cognitive status must be taken into account for elaboration of individualized patient-centered programs of rehabilitation after CABG.