Результаты исследований: Научные публикации в периодических изданиях › статья › Рецензирование
Polyacetylene Derivatives from the Polypore Fungus Fistulina hepatica (Agaricomycetes) and their Antimicrobial Activity. / Whaley, Anastasiia; Whaley, Andrei; Orlova, Anastasia; Volobuev, Sergey; Shakhova, Natalia; Smirnov, Sergey; Pustovit, Natalia; Kraeva, Liudmila.
в: International Journal of Medicinal Mushrooms, Том 25, № 12, 12.2023, стр. 43-53.Результаты исследований: Научные публикации в периодических изданиях › статья › Рецензирование
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TY - JOUR
T1 - Polyacetylene Derivatives from the Polypore Fungus Fistulina hepatica (Agaricomycetes) and their Antimicrobial Activity
AU - Whaley, Anastasiia
AU - Whaley, Andrei
AU - Orlova, Anastasia
AU - Volobuev, Sergey
AU - Shakhova, Natalia
AU - Smirnov, Sergey
AU - Pustovit, Natalia
AU - Kraeva, Liudmila
PY - 2023/12
Y1 - 2023/12
N2 - Chemical investigation of the polypore fungus Fistulina hepatica resulted in the isolation of five compounds, including four new polyacetylenic fatty acid derivatives - isocinnatriacetin B (1), isocinnatriacetin A (2), cinna-triacetin C (3) and ethylcinnatriacetin A (4) together with one known polyacetylene fatty acid derivative - cinnatriacetin A (5). The structures were elucidated using spectroscopic methods (UV, NMR, HR-ESIMS) along with comparison to literature data. Antibacterial activity screening of compounds 1-5 against ESKAPE bacterial strains in vitro with zones of inhibition (ZOI) was performed and MIC values were established for the most active compounds (3 and 4). Together with that morphological and growth parameters under solid-phase cultivation were also researched.
AB - Chemical investigation of the polypore fungus Fistulina hepatica resulted in the isolation of five compounds, including four new polyacetylenic fatty acid derivatives - isocinnatriacetin B (1), isocinnatriacetin A (2), cinna-triacetin C (3) and ethylcinnatriacetin A (4) together with one known polyacetylene fatty acid derivative - cinnatriacetin A (5). The structures were elucidated using spectroscopic methods (UV, NMR, HR-ESIMS) along with comparison to literature data. Antibacterial activity screening of compounds 1-5 against ESKAPE bacterial strains in vitro with zones of inhibition (ZOI) was performed and MIC values were established for the most active compounds (3 and 4). Together with that morphological and growth parameters under solid-phase cultivation were also researched.
UR - https://www.mendeley.com/catalogue/108ec456-9944-3690-ab2f-240d370fa995/
U2 - 10.1615/intjmedmushrooms.2023050525
DO - 10.1615/intjmedmushrooms.2023050525
M3 - Article
VL - 25
SP - 43
EP - 53
JO - International Journal of Medicinal Mushrooms
JF - International Journal of Medicinal Mushrooms
SN - 1521-9437
IS - 12
ER -
ID: 111860107