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Peptide from NSP7 is able to form amyloid-like fibrils: Artifact or challenge to drug design? / Garmay, Yuri; Rubel, Aleksandr A.; Egorov, Vladimir V.

в: BBA - Proteins and Proteomics, Том 1871, № 2, 140884, 01.02.2023.

Результаты исследований: Научные публикации в периодических изданияхстатьяРецензирование

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Garmay, Yuri ; Rubel, Aleksandr A. ; Egorov, Vladimir V. / Peptide from NSP7 is able to form amyloid-like fibrils: Artifact or challenge to drug design?. в: BBA - Proteins and Proteomics. 2023 ; Том 1871, № 2.

BibTeX

@article{c21c928e5b114fa09b8a56442fd129aa,
title = "Peptide from NSP7 is able to form amyloid-like fibrils: Artifact or challenge to drug design?",
abstract = "• We found potential amyloidogenic fragment in NSP7 SARS-CoV2 protein in silico. • NSP7 (52–62) fragment is able to form amyloid-like fibrils. • The possibility of using such a peptide as the basis for an antiviral drug is discussed. ",
keywords = "Amyloidogenic peptides, Antiviral peptides, NSP7, SARS-CoV-2",
author = "Yuri Garmay and Rubel, {Aleksandr A.} and Egorov, {Vladimir V.}",
note = "Publisher Copyright: {\textcopyright} 2022 Elsevier B.V.",
year = "2023",
month = feb,
day = "1",
doi = "10.1016/j.bbapap.2022.140884",
language = "English",
volume = "1871",
journal = "Biochimica et Biophysica Acta - Proteins and Proteomics",
issn = "1570-9639",
publisher = "Elsevier",
number = "2",

}

RIS

TY - JOUR

T1 - Peptide from NSP7 is able to form amyloid-like fibrils: Artifact or challenge to drug design?

AU - Garmay, Yuri

AU - Rubel, Aleksandr A.

AU - Egorov, Vladimir V.

N1 - Publisher Copyright: © 2022 Elsevier B.V.

PY - 2023/2/1

Y1 - 2023/2/1

N2 - • We found potential amyloidogenic fragment in NSP7 SARS-CoV2 protein in silico. • NSP7 (52–62) fragment is able to form amyloid-like fibrils. • The possibility of using such a peptide as the basis for an antiviral drug is discussed.

AB - • We found potential amyloidogenic fragment in NSP7 SARS-CoV2 protein in silico. • NSP7 (52–62) fragment is able to form amyloid-like fibrils. • The possibility of using such a peptide as the basis for an antiviral drug is discussed.

KW - Amyloidogenic peptides

KW - Antiviral peptides

KW - NSP7

KW - SARS-CoV-2

UR - http://www.scopus.com/inward/record.url?scp=85143861338&partnerID=8YFLogxK

U2 - 10.1016/j.bbapap.2022.140884

DO - 10.1016/j.bbapap.2022.140884

M3 - Article

C2 - 36462605

VL - 1871

JO - Biochimica et Biophysica Acta - Proteins and Proteomics

JF - Biochimica et Biophysica Acta - Proteins and Proteomics

SN - 1570-9639

IS - 2

M1 - 140884

ER -

ID: 100827733