Результаты исследований: Научные публикации в периодических изданиях › статья › Рецензирование
Peptide from NSP7 is able to form amyloid-like fibrils: Artifact or challenge to drug design? / Garmay, Yuri; Rubel, Aleksandr A.; Egorov, Vladimir V.
в: BBA - Proteins and Proteomics, Том 1871, № 2, 140884, 01.02.2023.Результаты исследований: Научные публикации в периодических изданиях › статья › Рецензирование
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TY - JOUR
T1 - Peptide from NSP7 is able to form amyloid-like fibrils: Artifact or challenge to drug design?
AU - Garmay, Yuri
AU - Rubel, Aleksandr A.
AU - Egorov, Vladimir V.
N1 - Publisher Copyright: © 2022 Elsevier B.V.
PY - 2023/2/1
Y1 - 2023/2/1
N2 - • We found potential amyloidogenic fragment in NSP7 SARS-CoV2 protein in silico. • NSP7 (52–62) fragment is able to form amyloid-like fibrils. • The possibility of using such a peptide as the basis for an antiviral drug is discussed.
AB - • We found potential amyloidogenic fragment in NSP7 SARS-CoV2 protein in silico. • NSP7 (52–62) fragment is able to form amyloid-like fibrils. • The possibility of using such a peptide as the basis for an antiviral drug is discussed.
KW - Amyloidogenic peptides
KW - Antiviral peptides
KW - NSP7
KW - SARS-CoV-2
UR - http://www.scopus.com/inward/record.url?scp=85143861338&partnerID=8YFLogxK
U2 - 10.1016/j.bbapap.2022.140884
DO - 10.1016/j.bbapap.2022.140884
M3 - Article
C2 - 36462605
VL - 1871
JO - Biochimica et Biophysica Acta - Proteins and Proteomics
JF - Biochimica et Biophysica Acta - Proteins and Proteomics
SN - 1570-9639
IS - 2
M1 - 140884
ER -
ID: 100827733