Molybdenum disulfide surface modification of ultrafine-grained titanium for enhanced cellular growth and antibacterial effect

Myeong Hwan Shin, Seung Mi Baek, Alexander V. Polyakov, Irina P. Semenova, Ruslan Z. Valiev, Woon Bong Hwang, Sei Kwang Hahn, Hyoung Seop Kim

Результат исследований: Научные публикации в периодических изданияхстатья

7 Цитирования (Scopus)

Аннотация

The commercially pure Ti (CP Ti) and equal-channel angular pressing (ECAP) processed Ti can contribute to the downsizing of medical devices with their superior mechanical properties and negligible toxicity. However, the ECAP-processed pure Ti has the risk of bacterial infection. Here, the coarse- and ultrafine-grained Ti substrates were surface-modified with molybdenum disulfide (MoS2) to improve the cell proliferation and growth with antibacterial effect for further dental applications. According to in vitro tests using the pre-osteoblast of MC3T3-E1 cell and a bacterial model of Escherichia coli (E. coli), MoS2 nanoflakes coated and ECAP-processed Ti substrates showed a significant increase in surface energy and singlet oxygen generation resulting in improved cell attachment and antibacterial effect. In addition, we confirmed the stability of the surface modified Ti substrates in a physiological solution and an artificial bone. Taken together, MoS2 modified and ECAP-processed Ti substrates might be successfully harnessed for various dental applications.

Язык оригиналаанглийский
Номер статьи9907
Число страниц10
ЖурналScientific Reports
Том8
Номер выпуска1
DOI
СостояниеОпубликовано - 2 июл 2018

Предметные области Scopus

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