Methyl methacrylate particles with amino groups on the surface: Colloid stability and sorption of biologically active substances

Vadim Baigildin, Galina Pankova, Tatyana Evseeva, Nikolay Lavrov, Irina Shirokova, Gleb Vaganov, Natalya Shevchenko

Результат исследований: Научные публикации в периодических изданияхстатьярецензирование

2 Цитирования (Scopus)

Аннотация

The present article investigates the influence of dispersion medium on the aggregate stability of cross-linked poly-(methyl methacrylate) particles on the surface layer of which aliphatic amino groups are localized. It is shown that particle size depends on the ionic strength of dispersion medium. The research determines the optimal content of cross-linked agent, ethylene glycol dimetharylate that results in the formation of cationic particles being stable in saline. Particle modification is performed by bovine serum albumin and luminophore fluorescein 5(6)-isothiocyanate. Protein sorption is observed not to influence luminescent properties of the particles. It is also determined that due to the aggregate stability of particles obtained from 5 wt% of ethylene glycol dimethacrylate in saline, the monodispersity and the absence of inversion of zeta potential in wide pH range is retained, such particles may be considered as perspective carriers of biologically active substances.

Язык оригиналаанглийский
Страницы (с-по)1570-1577
Число страниц8
ЖурналJournal of Dispersion Science and Technology
Том38
Номер выпуска11
DOI
СостояниеОпубликовано - 2 ноя 2017

Предметные области Scopus

  • Физическая и теоретическая химия
  • Поверхности, слои и пленки
  • Пластик и полимеры

Fingerprint Подробные сведения о темах исследования «Methyl methacrylate particles with amino groups on the surface: Colloid stability and sorption of biologically active substances». Вместе они формируют уникальный семантический отпечаток (fingerprint).

Цитировать