TY - JOUR

T1 - Komorbidnost' depressivnykh i trevozhnykh rasstroistv v klinicheskoi praktike

AU - Petrova, Natalia Nikolaevna

AU - Palkin, Yu R.

AU - Faddeev, D. V.

AU - Zinovieva, A. G.

N1 - Publisher Copyright: © 2021, Media Sphera Publishing Group. All rights reserved.

PY - 2021

Y1 - 2021

N2 - Objective. The study was the comparative characterization of depressed patients depending on the presence of comorbid anxiety. Material and methods. Thirty patients of the Clinic of neuroses named after acad. I.P. Pavlov Clinic of Neuroses. Comparison groups included 15 patients with comorbid anxiety and depressive disorders and 15 patients with depressive disorder without comorbid anxiety. The groups were comparable by sex and age. Clinical-catamnestic, clinical-therapeutic, and clinical-scale methods, including the Hamilton Depression and Anxiety Scales, were used during the study. Results. The structure of clinically diagnosed comorbid anxiety and depressive disorders was shown to be characterized by high representation of somato-vegetative symptoms and higher level of depression in comparison to depressive disorder without comorbid anxiety. According to psychometric assessment results, the level of anxiety did not differ in comparison groups, while clinically, according to ICD-10 criteria, anxiety was not diagnosed, indicating a discrepancy between clinical and scale assessments of anxiety and depressive disorders and greater accuracy of clinical and scale assessment of the condition. The effectiveness of combined treatment, including psychotropic therapy and psychotherapy, was lower in patients with comorbidity of anxiety and depression according to parameters of the degree of reduction of psychopathological symptoms, duration of treatment, and quality of remission. The structure of incomplete remission was similar in patients with comorbid anxiety and depressive disorders and depression. Conclusion. The obtained data suggest the expediency of continuous systematization of affective disorders and the need to improve the diagnostic criteria of comorbid anxiety and depressive disorders on the basis of combined clinical and scale assessment.

AB - Objective. The study was the comparative characterization of depressed patients depending on the presence of comorbid anxiety. Material and methods. Thirty patients of the Clinic of neuroses named after acad. I.P. Pavlov Clinic of Neuroses. Comparison groups included 15 patients with comorbid anxiety and depressive disorders and 15 patients with depressive disorder without comorbid anxiety. The groups were comparable by sex and age. Clinical-catamnestic, clinical-therapeutic, and clinical-scale methods, including the Hamilton Depression and Anxiety Scales, were used during the study. Results. The structure of clinically diagnosed comorbid anxiety and depressive disorders was shown to be characterized by high representation of somato-vegetative symptoms and higher level of depression in comparison to depressive disorder without comorbid anxiety. According to psychometric assessment results, the level of anxiety did not differ in comparison groups, while clinically, according to ICD-10 criteria, anxiety was not diagnosed, indicating a discrepancy between clinical and scale assessments of anxiety and depressive disorders and greater accuracy of clinical and scale assessment of the condition. The effectiveness of combined treatment, including psychotropic therapy and psychotherapy, was lower in patients with comorbidity of anxiety and depression according to parameters of the degree of reduction of psychopathological symptoms, duration of treatment, and quality of remission. The structure of incomplete remission was similar in patients with comorbid anxiety and depressive disorders and depression. Conclusion. The obtained data suggest the expediency of continuous systematization of affective disorders and the need to improve the diagnostic criteria of comorbid anxiety and depressive disorders on the basis of combined clinical and scale assessment.

KW - Anxiety

KW - Comorbidity

KW - Depression

KW - Diagnosis

KW - Therapy

KW - Anxiety/diagnosis

KW - Anxiety Disorders/diagnosis

KW - Comorbidity

KW - Depression/diagnosis

KW - Humans

KW - Treatment Outcome

UR - http://www.scopus.com/inward/record.url?scp=85107084643&partnerID=8YFLogxK

U2 - 10.17116/jnevro202112104131

DO - 10.17116/jnevro202112104131

M3 - статья

C2 - 34037352

AN - SCOPUS:85107084643

VL - 121

SP - 31

EP - 37

JO - ЖУРНАЛ НЕВРОЛОГИИ И ПСИХИАТРИИ ИМ. C.C. КОРСАКОВА

JF - ЖУРНАЛ НЕВРОЛОГИИ И ПСИХИАТРИИ ИМ. C.C. КОРСАКОВА

SN - 1997-7298

IS - 4

ER -