“Isocyanide-less” Ugi/Intramolecular Diels-Alder reaction of 5-hydroxymethylfurfural

Результат исследований: Научные публикации в периодических изданияхстатья

Выдержка

The one-pot, three-step, four-component Ugi-IMDAF reaction with 5-hydroxymethylfurfural provides simple access to hydroxymethyl-substituted epoxyisoindolones in a diastereoselective and stereospecific manner. The protocol avoids the transfer or isolation of isocyanides, and the broad scope was illustrated by the synthesis of 22 different compounds bearing various substituents on the heterocyclic core.

Язык оригиналаанглийский
Страницы (с-по)1578-1581
ЖурналTetrahedron Letters
Том60
Номер выпуска24
Ранняя дата в режиме онлайн20 мая 2019
DOI
СостояниеОпубликовано - 13 июн 2019

Отпечаток

Bearings (structural)
Cycloaddition Reaction
Cyanides
5-hydroxymethylfurfural

Предметные области Scopus

  • Поиск новых лекарств
  • Биохимия
  • Органическая химия

Цитировать

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abstract = "The one-pot, three-step, four-component Ugi-IMDAF reaction with 5-hydroxymethylfurfural provides simple access to hydroxymethyl-substituted epoxyisoindolones in a diastereoselective and stereospecific manner. The protocol avoids the transfer or isolation of isocyanides, and the broad scope was illustrated by the synthesis of 22 different compounds bearing various substituents on the heterocyclic core.",
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author = "Pavel Golubev and Alena Pankova and Mikhail Krasavin",
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“Isocyanide-less” Ugi/Intramolecular Diels-Alder reaction of 5-hydroxymethylfurfural. / Golubev, Pavel; Pankova, Alena; Krasavin, Mikhail.

В: Tetrahedron Letters, Том 60, № 24, 13.06.2019, стр. 1578-1581.

Результат исследований: Научные публикации в периодических изданияхстатья

TY - JOUR

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AU - Krasavin, Mikhail

PY - 2019/6/13

Y1 - 2019/6/13

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KW - 5-Hydroxymethylfurfural

KW - Diels-Alder reaction

KW - Isocyanide-based multicomponent reaction

KW - Ugi reaction

KW - PRODUCTS

KW - TRICYCLIC NITROGEN-HETEROCYCLES

KW - UGI REACTION

KW - SKELETAL

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JO - Tetrahedron Letters

JF - Tetrahedron Letters

SN - 0040-4039

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