Результаты исследований: Научные публикации в периодических изданиях › статья › Рецензирование
In vitro activity of fluoroquinolones, azithromycin and doxycycline against chlamydia trachomatis cultured from men with chronic lower urinary tract symptoms. / Smelov, V.; Perekalina, T.; Gorelov, A.; Smelova, N.; Artemenko, N.; Norman, L.
в: European Urology, Том 46, № 5, 01.11.2004, стр. 647-650.Результаты исследований: Научные публикации в периодических изданиях › статья › Рецензирование
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TY - JOUR
T1 - In vitro activity of fluoroquinolones, azithromycin and doxycycline against chlamydia trachomatis cultured from men with chronic lower urinary tract symptoms
AU - Smelov, V.
AU - Perekalina, T.
AU - Gorelov, A.
AU - Smelova, N.
AU - Artemenko, N.
AU - Norman, L.
PY - 2004/11/1
Y1 - 2004/11/1
N2 - Little is known about chlamydia survival in the presence of fluoroquinolones in patients with chronic prostatitis syndrome (CPS). In vitro activities of four fluoroquinolones, azithromycin and doxycycline against C. trachomatis in patients with CPS being not treated with antibiotics earlier were investigated and compared. Chlamydia survival in 304 patients with CPS being not treated with antibiotics earlier was analysed and compared. Infection by C. trachomatis was determined in the urethra and expressed prostatic secretion by cell culture test. Azithromycin and ofloxacin were found to be the most active antichlamydial agent with ciprofloxacin and doxycycline being least active. Ofloxacin can be recommended as the primary drug in the treatment of chlamydia-infected patients with CPS. The decision on the prescription of other fluoroquinolones should be made individually. The investigation of chlamydia survival in the presence of antibiotics in patients with CPS and C. trachomatis prior to treatment is recommended.
AB - Little is known about chlamydia survival in the presence of fluoroquinolones in patients with chronic prostatitis syndrome (CPS). In vitro activities of four fluoroquinolones, azithromycin and doxycycline against C. trachomatis in patients with CPS being not treated with antibiotics earlier were investigated and compared. Chlamydia survival in 304 patients with CPS being not treated with antibiotics earlier was analysed and compared. Infection by C. trachomatis was determined in the urethra and expressed prostatic secretion by cell culture test. Azithromycin and ofloxacin were found to be the most active antichlamydial agent with ciprofloxacin and doxycycline being least active. Ofloxacin can be recommended as the primary drug in the treatment of chlamydia-infected patients with CPS. The decision on the prescription of other fluoroquinolones should be made individually. The investigation of chlamydia survival in the presence of antibiotics in patients with CPS and C. trachomatis prior to treatment is recommended.
KW - Antibacterial treatment
KW - Chlamydia trachomatis
KW - Chronic prostatitis
KW - Fluoroquinolones
UR - http://www.scopus.com/inward/record.url?scp=5144234874&partnerID=8YFLogxK
U2 - 10.1016/j.eururo.2004.06.020
DO - 10.1016/j.eururo.2004.06.020
M3 - Article
C2 - 15474277
AN - SCOPUS:5144234874
VL - 46
SP - 647
EP - 650
JO - European Urology
JF - European Urology
SN - 0302-2838
IS - 5
ER -
ID: 39795590