Tandem repetitive sequences represent a significant part of many genomes but remain poorly characterized due to various methodological difficulties. Here, we describe the tandem repeat composition in the genome of zebra finch, Taeniopygia guttata, a species that has long served as an animal model, primarily in neurobiology and comparative genomics. Using available genome sequencing raw read datasets, we bioinformatically reconstructed consensus sequences of several tandem repeats and proved that the most abundant ones, Tgut191A and Tgut716A, are centromere-associated in chromosomes. Each centromeric region can have a different number of copies of each repeat, with Tgut716A enrichment in almost all microchromosomes and sex chromosomes. Sequences similar to Tgut191A and Tgut716A found in other Estrildidae and Viduidae species can be considered as candidate centromeric sequences, but this requires further cytogenetic verification.

Язык оригиналаанглийский
Страницы (с-по)55-63
Число страниц9
ЖурналCytogenetic and Genome Research
Номер выпуска1-2
Ранняя дата в режиме онлайн11 мар 2022
СостояниеОпубликовано - 1 июн 2022

Предметные области Scopus

  • Молекулярная биология
  • Генетика
  • Генетика (клиническая)


Подробные сведения о темах исследования «Identification of Centromere-Specific Repeats in the Zebra Finch Genome». Вместе они формируют уникальный семантический отпечаток (fingerprint).