Frequency-contrast sensitivity of visual stimulus perception in patients with schizophrenia treated with atypical and typical antipsychotics

I. I. Shoshina, Yu E. Shelepin, N. B. Semenova

Результат исследований: Научные публикации в периодических изданияхстатьярецензирование

6 Цитирования (Scopus)

Аннотация

The effects of typical and atypical antipsychotics on the perception of visual stimuli that preferentially activate magnocellular or parvocellular visual channels have been studied. The threshold contrast sensitivity in healthy individuals and patients with schizophrenia has been recorded. The Gabor-like sinusoidal brightness gratings and spatial frequencies of 0.4, 3.6, and 17.9 cycles/degree were presented to the tested objects. The patients were divided into two groups, one receiving the therapy with atypical antipsychotics, and the other, with typical ones. The contrast sensitivity for low and medium spatial frequencies (i.e., for the stimuli corresponding to magnocellular channels) decreased compared to the norm. Note that the decrease in the contrast sensitivity for the low spatial frequencies in the patients treated with atypical antipsychotics is significantly more pronounced compared to the cohort that received typical antipsychotics.

Язык оригиналаанглийский
Страницы (с-по)35-39
Число страниц5
ЖурналHuman Physiology
Том40
Номер выпуска1
DOI
СостояниеОпубликовано - 1 янв 2014

Предметные области Scopus

  • Физиология
  • Физиология (медицинская)

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