[Effect of superlow doses (10(-18)-10-(-14) M) of biologically active substances: general rules, features, and possible mechanisms].

L.A. Sazanov, S.V. Zaitsev

Результат исследований: Научные публикации в периодических изданияхстатьярецензирование

19 Цитирования (Scopus)


The effects of ultra-low (10(-18)-10(-14) M) doses (ULD) of biologically active substances have been reviewed in terms of common regularities of ULD effects and peculiarities of action of various groups of compounds. The most common and at the same time paradoxical regularities of ULD action are bi- or polymodal patterns of dose dependence, absence or presence of an inverse effect at higher doses, and instability of ULD effect. Possible mechanisms of ULD action including the mechanism based on the adaptation theory are discussed.
Язык оригиналарусский
Страницы (с-по)1443-1460
ЖурналBiochemistry (Moscow)
Номер выпуска10
СостояниеОпубликовано - 1992
Опубликовано для внешнего пользованияДа