Cyclic diazo compounds in the construction of spirocyclic scaffolds

Результат исследований: Научные публикации в периодических изданияхОбзорная статьярецензирование


Spirocycles represent an emerging class of privileged motifs for drug discovery. The versatility of diazo compounds in constructing cyclic frameworks in general makes cyclic diazo compounds a potentially highly prolific source of spirocyclic scaffolds. While the first examples of obtaining a spirocycle from a cyclic diazo compound are dated as far back as 42 years ago, there appears to be a resurgence of novel methodologies based on this premise. The present Digest Article aims to cover the literature on the subject to-date.

Язык оригиналаанглийский
Номер статьи152671
ЖурналTetrahedron Letters
СостояниеПринято в печать - 2020

Предметные области Scopus

  • Биохимия
  • Поиск новых лекарств
  • Органическая химия

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