Современные представления о контраст-индуцированном остром почечном повреждении

Взгляд интервенционного радиолога

Результат исследований: Научные публикации в периодических изданияхОбзорная статьянаучнаярецензирование

Выдержка

Clinically relevant contrast-induced acute kidney injury (CI-AKI) is a severe complication of
interventional contrast-based procedures of all kinds. It is linked to high morbidity, mortality, social and
fi nancial losses. Acute renal damage after coronary angiography or percutaneous coronary intervention
may occur in 1-2% cases in general population or in more than 50% of cases with high risk of developing
CI-AKI. It is very important to identify existing compromised renal function in a high-risk patient, as it is
a major and frequent CI-AKI predisposing factor. There are novel biomarkers with rapid or nearly instant
response to acute subclinical contrast-induced renal damage, which are highly valuable in CI-AKI diagnosis
and for this reason desire deeper clinical research. Despite a number of controversies, prophylactic and
therapeutic measures are practically the same in a vast majority of guidelines. Intravenous 0.9% NaCl
solution remains one and only proved measure in CI-AKI prophylaxis and therapy, while the use of other
pharmacological approaches still needs more relevant prospective clinical research. The aim of this paper
was review contemporary, CI-AKI-devoted, evidence-based data.
Язык оригиналарусский
Страницы (с-по)407-417
Число страниц10
ЖурналНЕФРОЛОГИЯ И ДИАЛИЗ
Том19
Номер выпуска3
СостояниеОпубликовано - окт 2017

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@article{482cbdda954348859f6526164a51153f,
title = "Современные представления о контраст-индуцированном остром почечном повреждении: Взгляд интервенционного радиолога",
abstract = "Clinically relevant contrast-induced acute kidney injury (CI-AKI) is a severe complication ofinterventional contrast-based procedures of all kinds. It is linked to high morbidity, mortality, social andfi nancial losses. Acute renal damage after coronary angiography or percutaneous coronary interventionmay occur in 1-2{\%} cases in general population or in more than 50{\%} of cases with high risk of developingCI-AKI. It is very important to identify existing compromised renal function in a high-risk patient, as it isa major and frequent CI-AKI predisposing factor. There are novel biomarkers with rapid or nearly instantresponse to acute subclinical contrast-induced renal damage, which are highly valuable in CI-AKI diagnosisand for this reason desire deeper clinical research. Despite a number of controversies, prophylactic andtherapeutic measures are practically the same in a vast majority of guidelines. Intravenous 0.9{\%} NaClsolution remains one and only proved measure in CI-AKI prophylaxis and therapy, while the use of otherpharmacological approaches still needs more relevant prospective clinical research. The aim of this paperwas review contemporary, CI-AKI-devoted, evidence-based data.",
keywords = "нефропатия, повреждение почек, контрастные вещества, биомаркеры почечного повреждения",
author = "Хильчук, {Антон Андреевич} and Щербак, {Сергей Григорьевич} and Сарана, {Андрей Михайлович} and Власенко, {Сергей Васильевич}",
year = "2017",
month = "10",
language = "русский",
volume = "19",
pages = "407--417",
journal = "Nephrology and Dialysis",
issn = "1680-4422",
publisher = "Российское диализное общество",
number = "3",

}

TY - JOUR

T1 - Современные представления о контраст-индуцированном остром почечном повреждении

T2 - Взгляд интервенционного радиолога

AU - Хильчук, Антон Андреевич

AU - Щербак, Сергей Григорьевич

AU - Сарана, Андрей Михайлович

AU - Власенко, Сергей Васильевич

PY - 2017/10

Y1 - 2017/10

N2 - Clinically relevant contrast-induced acute kidney injury (CI-AKI) is a severe complication ofinterventional contrast-based procedures of all kinds. It is linked to high morbidity, mortality, social andfi nancial losses. Acute renal damage after coronary angiography or percutaneous coronary interventionmay occur in 1-2% cases in general population or in more than 50% of cases with high risk of developingCI-AKI. It is very important to identify existing compromised renal function in a high-risk patient, as it isa major and frequent CI-AKI predisposing factor. There are novel biomarkers with rapid or nearly instantresponse to acute subclinical contrast-induced renal damage, which are highly valuable in CI-AKI diagnosisand for this reason desire deeper clinical research. Despite a number of controversies, prophylactic andtherapeutic measures are practically the same in a vast majority of guidelines. Intravenous 0.9% NaClsolution remains one and only proved measure in CI-AKI prophylaxis and therapy, while the use of otherpharmacological approaches still needs more relevant prospective clinical research. The aim of this paperwas review contemporary, CI-AKI-devoted, evidence-based data.

AB - Clinically relevant contrast-induced acute kidney injury (CI-AKI) is a severe complication ofinterventional contrast-based procedures of all kinds. It is linked to high morbidity, mortality, social andfi nancial losses. Acute renal damage after coronary angiography or percutaneous coronary interventionmay occur in 1-2% cases in general population or in more than 50% of cases with high risk of developingCI-AKI. It is very important to identify existing compromised renal function in a high-risk patient, as it isa major and frequent CI-AKI predisposing factor. There are novel biomarkers with rapid or nearly instantresponse to acute subclinical contrast-induced renal damage, which are highly valuable in CI-AKI diagnosisand for this reason desire deeper clinical research. Despite a number of controversies, prophylactic andtherapeutic measures are practically the same in a vast majority of guidelines. Intravenous 0.9% NaClsolution remains one and only proved measure in CI-AKI prophylaxis and therapy, while the use of otherpharmacological approaches still needs more relevant prospective clinical research. The aim of this paperwas review contemporary, CI-AKI-devoted, evidence-based data.

KW - нефропатия

KW - повреждение почек

KW - контрастные вещества

KW - биомаркеры почечного повреждения

M3 - Обзорная статья

VL - 19

SP - 407

EP - 417

JO - Nephrology and Dialysis

JF - Nephrology and Dialysis

SN - 1680-4422

IS - 3

ER -