Comparative analysis of the mitochondrial genomes of Orthonectida: insights into the evolution of an invertebrate parasite species

Результат исследований: Научные публикации в периодических изданияхстатьянаучнаярецензирование

3 Цитирования (Scopus)

Выдержка

Among invertebrates, only a few groups still have uncertain phylogenetic position, Orthonectida, a small group of rare multi-cellular parasites of marine invertebrates, being one of them. Recent molecular and morphological findings suggest that orthonectids belong to Lophotrochozoa and are close to Annelida. Nevertheless, phylogenetic relationships between orthonectids and annelids are unclear, and the phylogeny within the group itself has never been studied. Sequencing of mitochondrial genomes is used here to clarify this issue. Complete mt genomes of the orthonectids Intoshia variabili and Rhopalura litoralis were characterized and compared with Intoshia linei mt genome. Our results show that Orthonectida mt genomes have undergone reduction and gene loss, and that they have complicated organization revealed in strand asymmetry in nucleotide composition, in some features of intergenic non-coding regions, tRNA duplication and folding. Moreover, all species of Orthonectida have a unique gene order with complicated rearrangement landscape. Significant differences in mitochondrial genomes in the three orthonectid species could be explained by the fact that their host species belong to different taxa (flat worms, nemertines and gastropods). Among the analyzed mt genomes of Orthonectida, I. linei possesses the closest gene order to the ancestral genome. All Orthonectida species are monophyletic, and in the phylogenetic tree are close to Pleistoannelida, and specifically, to Clitellata.

Язык оригиналаанглийский
Страницы (с-по)715-727
Число страниц13
ЖурналMolecular Genetics and Genomics
Том294
Номер выпуска3
Ранняя дата в режиме онлайн8 мар 2019
DOI
СостояниеОпубликовано - июн 2019

Предметные области Scopus

  • Генетика
  • Молекулярная биология

Цитировать

@article{00560248a1a94f588f65575306e3963c,
title = "Comparative analysis of the mitochondrial genomes of Orthonectida: insights into the evolution of an invertebrate parasite species",
abstract = "Among invertebrates, only a few groups still have uncertain phylogenetic position, Orthonectida, a small group of rare multi-cellular parasites of marine invertebrates, being one of them. Recent molecular and morphological findings suggest that orthonectids belong to Lophotrochozoa and are close to Annelida. Nevertheless, phylogenetic relationships between orthonectids and annelids are unclear, and the phylogeny within the group itself has never been studied. Sequencing of mitochondrial genomes is used here to clarify this issue. Complete mt genomes of the orthonectids Intoshia variabili and Rhopalura litoralis were characterized and compared with Intoshia linei mt genome. Our results show that Orthonectida mt genomes have undergone reduction and gene loss, and that they have complicated organization revealed in strand asymmetry in nucleotide composition, in some features of intergenic non-coding regions, tRNA duplication and folding. Moreover, all species of Orthonectida have a unique gene order with complicated rearrangement landscape. Significant differences in mitochondrial genomes in the three orthonectid species could be explained by the fact that their host species belong to different taxa (flat worms, nemertines and gastropods). Among the analyzed mt genomes of Orthonectida, I. linei possesses the closest gene order to the ancestral genome. All Orthonectida species are monophyletic, and in the phylogenetic tree are close to Pleistoannelida, and specifically, to Clitellata.",
keywords = "Gene order, Mitochondrial DNA, Mitochondrial genome, Mitochondrion genome rearrangements, Orthonectida, ALIGNMENT, MITOGENOMICS, SEQUENCE, MODEL",
author = "N. Bondarenko and A. Bondarenko and V. Starunov and G. Slyusarev",
year = "2019",
month = "6",
doi = "10.1007/s00438-019-01543-1",
language = "English",
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issn = "1617-4615",
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Comparative analysis of the mitochondrial genomes of Orthonectida: insights into the evolution of an invertebrate parasite species. / Bondarenko, N.; Bondarenko, A.; Starunov, V.; Slyusarev, G.

В: Molecular Genetics and Genomics, Том 294, № 3, 06.2019, стр. 715-727.

Результат исследований: Научные публикации в периодических изданияхстатьянаучнаярецензирование

TY - JOUR

T1 - Comparative analysis of the mitochondrial genomes of Orthonectida: insights into the evolution of an invertebrate parasite species

AU - Bondarenko, N.

AU - Bondarenko, A.

AU - Starunov, V.

AU - Slyusarev, G.

PY - 2019/6

Y1 - 2019/6

N2 - Among invertebrates, only a few groups still have uncertain phylogenetic position, Orthonectida, a small group of rare multi-cellular parasites of marine invertebrates, being one of them. Recent molecular and morphological findings suggest that orthonectids belong to Lophotrochozoa and are close to Annelida. Nevertheless, phylogenetic relationships between orthonectids and annelids are unclear, and the phylogeny within the group itself has never been studied. Sequencing of mitochondrial genomes is used here to clarify this issue. Complete mt genomes of the orthonectids Intoshia variabili and Rhopalura litoralis were characterized and compared with Intoshia linei mt genome. Our results show that Orthonectida mt genomes have undergone reduction and gene loss, and that they have complicated organization revealed in strand asymmetry in nucleotide composition, in some features of intergenic non-coding regions, tRNA duplication and folding. Moreover, all species of Orthonectida have a unique gene order with complicated rearrangement landscape. Significant differences in mitochondrial genomes in the three orthonectid species could be explained by the fact that their host species belong to different taxa (flat worms, nemertines and gastropods). Among the analyzed mt genomes of Orthonectida, I. linei possesses the closest gene order to the ancestral genome. All Orthonectida species are monophyletic, and in the phylogenetic tree are close to Pleistoannelida, and specifically, to Clitellata.

AB - Among invertebrates, only a few groups still have uncertain phylogenetic position, Orthonectida, a small group of rare multi-cellular parasites of marine invertebrates, being one of them. Recent molecular and morphological findings suggest that orthonectids belong to Lophotrochozoa and are close to Annelida. Nevertheless, phylogenetic relationships between orthonectids and annelids are unclear, and the phylogeny within the group itself has never been studied. Sequencing of mitochondrial genomes is used here to clarify this issue. Complete mt genomes of the orthonectids Intoshia variabili and Rhopalura litoralis were characterized and compared with Intoshia linei mt genome. Our results show that Orthonectida mt genomes have undergone reduction and gene loss, and that they have complicated organization revealed in strand asymmetry in nucleotide composition, in some features of intergenic non-coding regions, tRNA duplication and folding. Moreover, all species of Orthonectida have a unique gene order with complicated rearrangement landscape. Significant differences in mitochondrial genomes in the three orthonectid species could be explained by the fact that their host species belong to different taxa (flat worms, nemertines and gastropods). Among the analyzed mt genomes of Orthonectida, I. linei possesses the closest gene order to the ancestral genome. All Orthonectida species are monophyletic, and in the phylogenetic tree are close to Pleistoannelida, and specifically, to Clitellata.

KW - Gene order

KW - Mitochondrial DNA

KW - Mitochondrial genome

KW - Mitochondrion genome rearrangements

KW - Orthonectida

KW - ALIGNMENT

KW - MITOGENOMICS

KW - SEQUENCE

KW - MODEL

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UR - http://www.mendeley.com/research/comparative-analysis-mitochondrial-genomes-orthonectida-insights-evolution-invertebrate-parasite-spe

U2 - 10.1007/s00438-019-01543-1

DO - 10.1007/s00438-019-01543-1

M3 - Article

VL - 294

SP - 715

EP - 727

JO - Molecular Genetics and Genomics

JF - Molecular Genetics and Genomics

SN - 1617-4615

IS - 3

ER -