Collapsed monomolecular thin films as surface nanomodification techniques for bioorganic MALDI analysis

E.S. Silyavka; A.A. Selyutin; N.G. Sukhodolov; V.V. Shilovskikh; P.A. Oleneva; A.A. Mitrofanov; O.A. Keltsieva; P.S. Dubakova; V.N. Babakov; M.L. Alexandrova; N.V. Krasnov; E.P. Podolskaya

doi:10.1063/1.5087677

Collapsed monomolecular thin films as surface nanomodification techniques for bioorganic MALDI analysis

E.S. Silyavka, A.A. Selyutin, N.G. Sukhodolov, V.V. Shilovskikh, P.A. Oleneva, A.A. Mitrofanov, O.A. Keltsieva, P.S. Dubakova, V.N. Babakov, M.L. Alexandrova, N.V. Krasnov, E.P. Podolskaya

Результат исследований: Публикации в книгах, отчётах, сборниках, трудах конференций › статья в сборнике материалов конференции › научная › рецензирование

Аннотация

A modification method of the target for Matrix Assisted Laser Desorption/Ionization (MALDI) analysis by metal-affinity sorbents was proposed. Monolayers of metal stearates obtained in the geometry of the drop perform as such sorbents. The formation of monolayers was proved by optical microscopy and the Laser Desorption/Ionization (LDI) method. The surface of the substrate after modification studied using scanning electron microscopy. Metal-affinity extraction of human serum albumin adducts with soman was carried out at the modified target surface. MALDI mass spectrometric analysis demonstrated that signals corresponding to adducts are present in mass spectra.

Язык оригинала	английский
Название основной публикации	International Conference on State-of-the-Art Trends of Scientific Research of Artificial and Natural Nanoobjects, STRANN 2018
Издатель	American Institute of Physics
ISBN (печатное издание)	9780735417922
DOI	https://doi.org/10.1063/1.5087677
Состояние	Опубликовано - 15 янв 2019
Событие	International Conference on State-of-the-Art Trends of Scientific Research of Artificial and Natural Nanoobjects, STRANN 2018 - Moscow, Российская Федерация Продолжительность: 17 окт 2018 → 19 окт 2018

Серия публикаций

Название	AIP Conference Proceedings
Издатель	American Institute of Physics
Номер	1
Том	2064
ISSN (печатное издание)	0094-243X

Конференция

Конференция	International Conference on State-of-the-Art Trends of Scientific Research of Artificial and Natural Nanoobjects, STRANN 2018
Страна	Российская Федерация
Город	Moscow
Период	17/10/18 → 19/10/18

Предметные области Scopus

Физика и астрономия (все)

Доступ к документу

10.1063/1.5087677

http://www.scopus.com/inward/record.url?scp=85060536398&partnerID=8YFLogxK

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Цитировать

Silyavka, E. S., Selyutin, A. A., Sukhodolov, N. G., Shilovskikh, V. V., Oleneva, P. A., Mitrofanov, A. A., Keltsieva, O. A., Dubakova, P. S., Babakov, V. N., Alexandrova, M. L., Krasnov, N. V., & Podolskaya, E. P. (2019). Collapsed monomolecular thin films as surface nanomodification techniques for bioorganic MALDI analysis. В International Conference on State-of-the-Art Trends of Scientific Research of Artificial and Natural Nanoobjects, STRANN 2018 [030015] (AIP Conference Proceedings; Том 2064, № 1). American Institute of Physics. https://doi.org/10.1063/1.5087677

Silyavka, E.S. ; Selyutin, A.A. ; Sukhodolov, N.G. ; Shilovskikh, V.V. ; Oleneva, P.A. ; Mitrofanov, A.A. ; Keltsieva, O.A. ; Dubakova, P.S. ; Babakov, V.N. ; Alexandrova, M.L. ; Krasnov, N.V. ; Podolskaya, E.P. / Collapsed monomolecular thin films as surface nanomodification techniques for bioorganic MALDI analysis. International Conference on State-of-the-Art Trends of Scientific Research of Artificial and Natural Nanoobjects, STRANN 2018. American Institute of Physics, 2019. (AIP Conference Proceedings; 1).

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title = "Collapsed monomolecular thin films as surface nanomodification techniques for bioorganic MALDI analysis",

abstract = "A modification method of the target for Matrix Assisted Laser Desorption/Ionization (MALDI) analysis by metal-affinity sorbents was proposed. Monolayers of metal stearates obtained in the geometry of the drop perform as such sorbents. The formation of monolayers was proved by optical microscopy and the Laser Desorption/Ionization (LDI) method. The surface of the substrate after modification studied using scanning electron microscopy. Metal-affinity extraction of human serum albumin adducts with soman was carried out at the modified target surface. MALDI mass spectrometric analysis demonstrated that signals corresponding to adducts are present in mass spectra.",

author = "E.S. Silyavka and A.A. Selyutin and N.G. Sukhodolov and V.V. Shilovskikh and P.A. Oleneva and A.A. Mitrofanov and O.A. Keltsieva and P.S. Dubakova and V.N. Babakov and M.L. Alexandrova and N.V. Krasnov and E.P. Podolskaya",

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publisher = "American Institute of Physics",

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booktitle = "International Conference on State-of-the-Art Trends of Scientific Research of Artificial and Natural Nanoobjects, STRANN 2018",

address = "United States",

note = "International Conference on State-of-the-Art Trends of Scientific Research of Artificial and Natural Nanoobjects, STRANN 2018 ; Conference date: 17-10-2018 Through 19-10-2018",

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Silyavka, ES , Selyutin, AA , Sukhodolov, NG, Shilovskikh, VV, Oleneva, PA , Mitrofanov, AA, Keltsieva, OA, Dubakova, PS, Babakov, VN, Alexandrova, ML, Krasnov, NV & Podolskaya, EP 2019, Collapsed monomolecular thin films as surface nanomodification techniques for bioorganic MALDI analysis. в International Conference on State-of-the-Art Trends of Scientific Research of Artificial and Natural Nanoobjects, STRANN 2018., 030015, AIP Conference Proceedings, № 1, том. 2064, American Institute of Physics, International Conference on State-of-the-Art Trends of Scientific Research of Artificial and Natural Nanoobjects, STRANN 2018, Moscow, Российская Федерация, 17/10/18. https://doi.org/10.1063/1.5087677

Collapsed monomolecular thin films as surface nanomodification techniques for bioorganic MALDI analysis. / Silyavka, E.S.; Selyutin, A.A.; Sukhodolov, N.G.; Shilovskikh, V.V.; Oleneva, P.A.; Mitrofanov, A.A.; Keltsieva, O.A.; Dubakova, P.S.; Babakov, V.N.; Alexandrova, M.L.; Krasnov, N.V.; Podolskaya, E.P.

International Conference on State-of-the-Art Trends of Scientific Research of Artificial and Natural Nanoobjects, STRANN 2018. American Institute of Physics, 2019. 030015 (AIP Conference Proceedings; Том 2064, № 1).

Результат исследований: Публикации в книгах, отчётах, сборниках, трудах конференций › статья в сборнике материалов конференции › научная › рецензирование

TY - GEN

T1 - Collapsed monomolecular thin films as surface nanomodification techniques for bioorganic MALDI analysis

AU - Silyavka, E.S.

AU - Selyutin, A.A.

AU - Sukhodolov, N.G.

AU - Shilovskikh, V.V.

AU - Oleneva, P.A.

AU - Mitrofanov, A.A.

AU - Keltsieva, O.A.

AU - Dubakova, P.S.

AU - Babakov, V.N.

AU - Alexandrova, M.L.

AU - Krasnov, N.V.

AU - Podolskaya, E.P.

PY - 2019/1/15

Y1 - 2019/1/15

N2 - A modification method of the target for Matrix Assisted Laser Desorption/Ionization (MALDI) analysis by metal-affinity sorbents was proposed. Monolayers of metal stearates obtained in the geometry of the drop perform as such sorbents. The formation of monolayers was proved by optical microscopy and the Laser Desorption/Ionization (LDI) method. The surface of the substrate after modification studied using scanning electron microscopy. Metal-affinity extraction of human serum albumin adducts with soman was carried out at the modified target surface. MALDI mass spectrometric analysis demonstrated that signals corresponding to adducts are present in mass spectra.

AB - A modification method of the target for Matrix Assisted Laser Desorption/Ionization (MALDI) analysis by metal-affinity sorbents was proposed. Monolayers of metal stearates obtained in the geometry of the drop perform as such sorbents. The formation of monolayers was proved by optical microscopy and the Laser Desorption/Ionization (LDI) method. The surface of the substrate after modification studied using scanning electron microscopy. Metal-affinity extraction of human serum albumin adducts with soman was carried out at the modified target surface. MALDI mass spectrometric analysis demonstrated that signals corresponding to adducts are present in mass spectra.

UR - http://www.scopus.com/inward/record.url?scp=85060536398&partnerID=8YFLogxK

U2 - 10.1063/1.5087677

DO - 10.1063/1.5087677

M3 - Conference contribution

SN - 9780735417922

T3 - AIP Conference Proceedings

BT - International Conference on State-of-the-Art Trends of Scientific Research of Artificial and Natural Nanoobjects, STRANN 2018

PB - American Institute of Physics

T2 - International Conference on State-of-the-Art Trends of Scientific Research of Artificial and Natural Nanoobjects, STRANN 2018

Y2 - 17 October 2018 through 19 October 2018

ER -

Silyavka ES , Selyutin AA , Sukhodolov NG, Shilovskikh VV, Oleneva PA , Mitrofanov AA и соавт. Collapsed monomolecular thin films as surface nanomodification techniques for bioorganic MALDI analysis. В International Conference on State-of-the-Art Trends of Scientific Research of Artificial and Natural Nanoobjects, STRANN 2018. American Institute of Physics. 2019. 030015. (AIP Conference Proceedings; 1). https://doi.org/10.1063/1.5087677