Выдержка
A modification method of the target for Matrix Assisted Laser Desorption/Ionization (MALDI) analysis by metal-affinity sorbents was proposed. Monolayers of metal stearates obtained in the geometry of the drop perform as such sorbents. The formation of monolayers was proved by optical microscopy and the Laser Desorption/Ionization (LDI) method. The surface of the substrate after modification studied using scanning electron microscopy. Metal-affinity extraction of human serum albumin adducts with soman was carried out at the modified target surface. MALDI mass spectrometric analysis demonstrated that signals corresponding to adducts are present in mass spectra.
| Язык оригинала | английский |
|---|---|
| Название основной публикации | International Conference on State-of-the-Art Trends of Scientific Research of Artificial and Natural Nanoobjects, STRANN 2018 |
| Издатель | American Institute of Physics |
| ISBN (печатное издание) | 9780735417922 |
| DOI | |
| Состояние | Опубликовано - 15 янв 2019 |
| Событие | International Conference on State-of-the-Art Trends of Scientific Research of Artificial and Natural Nanoobjects, STRANN 2018 - Moscow, Российская Федерация Продолжительность: 17 окт 2018 → 19 окт 2018 |
Серия публикаций
| Название | AIP Conference Proceedings |
|---|---|
| Издатель | American Institute of Physics |
| Номер | 1 |
| Том | 2064 |
| ISSN (печатное издание) | 0094-243X |
Конференция
| Конференция | International Conference on State-of-the-Art Trends of Scientific Research of Artificial and Natural Nanoobjects, STRANN 2018 |
|---|---|
| Страна | Российская Федерация |
| Город | Moscow |
| Период | 17/10/18 → 19/10/18 |
Отпечаток
Предметные области Scopus
- Физика и астрономия (все)
Цитировать
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Collapsed monomolecular thin films as surface nanomodification techniques for bioorganic MALDI analysis. / Silyavka, E.S.; Selyutin, A.A.; Sukhodolov, N.G.; Shilovskikh, V.V.; Oleneva, P.A.; Mitrofanov, A.A.; Keltsieva, O.A.; Dubakova, P.S.; Babakov, V.N.; Alexandrova, M.L.; Krasnov, N.V.; Podolskaya, E.P.
International Conference on State-of-the-Art Trends of Scientific Research of Artificial and Natural Nanoobjects, STRANN 2018. American Institute of Physics, 2019. 030015 (AIP Conference Proceedings; Том 2064, № 1).Результат исследований: Публикации в книгах, отчётах, сборниках, трудах конференций › статья в сборнике материалов конференции › научная › рецензирование
TY - GEN
T1 - Collapsed monomolecular thin films as surface nanomodification techniques for bioorganic MALDI analysis
AU - Silyavka, E.S.
AU - Selyutin, A.A.
AU - Sukhodolov, N.G.
AU - Shilovskikh, V.V.
AU - Oleneva, P.A.
AU - Mitrofanov, A.A.
AU - Keltsieva, O.A.
AU - Dubakova, P.S.
AU - Babakov, V.N.
AU - Alexandrova, M.L.
AU - Krasnov, N.V.
AU - Podolskaya, E.P.
PY - 2019/1/15
Y1 - 2019/1/15
N2 - A modification method of the target for Matrix Assisted Laser Desorption/Ionization (MALDI) analysis by metal-affinity sorbents was proposed. Monolayers of metal stearates obtained in the geometry of the drop perform as such sorbents. The formation of monolayers was proved by optical microscopy and the Laser Desorption/Ionization (LDI) method. The surface of the substrate after modification studied using scanning electron microscopy. Metal-affinity extraction of human serum albumin adducts with soman was carried out at the modified target surface. MALDI mass spectrometric analysis demonstrated that signals corresponding to adducts are present in mass spectra.
AB - A modification method of the target for Matrix Assisted Laser Desorption/Ionization (MALDI) analysis by metal-affinity sorbents was proposed. Monolayers of metal stearates obtained in the geometry of the drop perform as such sorbents. The formation of monolayers was proved by optical microscopy and the Laser Desorption/Ionization (LDI) method. The surface of the substrate after modification studied using scanning electron microscopy. Metal-affinity extraction of human serum albumin adducts with soman was carried out at the modified target surface. MALDI mass spectrometric analysis demonstrated that signals corresponding to adducts are present in mass spectra.
UR - http://www.scopus.com/inward/record.url?scp=85060536398&partnerID=8YFLogxK
U2 - 10.1063/1.5087677
DO - 10.1063/1.5087677
M3 - Conference contribution
SN - 9780735417922
T3 - AIP Conference Proceedings
BT - International Conference on State-of-the-Art Trends of Scientific Research of Artificial and Natural Nanoobjects, STRANN 2018
PB - American Institute of Physics
ER -