Characterization of missense mutations in the SUP45 gene of Saccharomyces cerevisiae encoding translation termination factor eRF1

S. E. Moskalenko, G. A. Zhouravleva, M. Y. Soom, S. V. Chabelskaya, K. V. Volkov, O. M. Zemlyanko, M. Philippe, L. N. Mironova, S. G. Inge-Vechtomov

Результат исследований: Научные публикации в периодических изданияхстатья

4 Цитирования (Scopus)

Выдержка

Collection of missense mutations in the SUP45 gene of Saccharomyces cerevisiae encoding translation termination factor eRF1 has been obtained by different approaches. It has been shown that most of isolated mutations cause amino acid substitutions in the N-terminal part of eRF1 and do not decrease the eRF1 amount. Most of mutations studied do not abolish eRF1-eRF3 interaction. The role of the N-terminal part of eRF1 in stop codon recognition is discussed.

Язык оригиналаанглийский
Страницы (с-по)478-484
Число страниц7
ЖурналRussian Journal of Genetics
Том40
Номер выпуска5
DOI
СостояниеОпубликовано - 1 мая 2004

Отпечаток

Missense Mutation
Saccharomyces cerevisiae
Mutation
Terminator Codon
Amino Acid Substitution
Genes

Предметные области Scopus

  • Генетика

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abstract = "Collection of missense mutations in the SUP45 gene of Saccharomyces cerevisiae encoding translation termination factor eRF1 has been obtained by different approaches. It has been shown that most of isolated mutations cause amino acid substitutions in the N-terminal part of eRF1 and do not decrease the eRF1 amount. Most of mutations studied do not abolish eRF1-eRF3 interaction. The role of the N-terminal part of eRF1 in stop codon recognition is discussed.",
author = "Moskalenko, {S. E.} and Zhouravleva, {G. A.} and Soom, {M. Y.} and Chabelskaya, {S. V.} and Volkov, {K. V.} and Zemlyanko, {O. M.} and M. Philippe and Mironova, {L. N.} and Inge-Vechtomov, {S. G.}",
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Characterization of missense mutations in the SUP45 gene of Saccharomyces cerevisiae encoding translation termination factor eRF1. / Moskalenko, S. E.; Zhouravleva, G. A.; Soom, M. Y.; Chabelskaya, S. V.; Volkov, K. V.; Zemlyanko, O. M.; Philippe, M.; Mironova, L. N.; Inge-Vechtomov, S. G.

В: Russian Journal of Genetics, Том 40, № 5, 01.05.2004, стр. 478-484.

Результат исследований: Научные публикации в периодических изданияхстатья

TY - JOUR

T1 - Characterization of missense mutations in the SUP45 gene of Saccharomyces cerevisiae encoding translation termination factor eRF1

AU - Moskalenko, S. E.

AU - Zhouravleva, G. A.

AU - Soom, M. Y.

AU - Chabelskaya, S. V.

AU - Volkov, K. V.

AU - Zemlyanko, O. M.

AU - Philippe, M.

AU - Mironova, L. N.

AU - Inge-Vechtomov, S. G.

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AB - Collection of missense mutations in the SUP45 gene of Saccharomyces cerevisiae encoding translation termination factor eRF1 has been obtained by different approaches. It has been shown that most of isolated mutations cause amino acid substitutions in the N-terminal part of eRF1 and do not decrease the eRF1 amount. Most of mutations studied do not abolish eRF1-eRF3 interaction. The role of the N-terminal part of eRF1 in stop codon recognition is discussed.

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