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Autoaggressive immunocompetent cells in mice in the late stages after irradiation. / Klimovich, V. B.; Samoilovich, M. P.

в: Bulletin of Experimental Biology and Medicine, Том 85, № 4, 04.1978, стр. 495-497.

Результаты исследований: Научные публикации в периодических изданиях › статья › Рецензирование

Harvard

Klimovich, VB & Samoilovich, MP 1978, 'Autoaggressive immunocompetent cells in mice in the late stages after irradiation', Bulletin of Experimental Biology and Medicine, Том. 85, № 4, стр. 495-497. https://doi.org/10.1007/BF00801994

APA

Klimovich, V. B., & Samoilovich, M. P. (1978). Autoaggressive immunocompetent cells in mice in the late stages after irradiation. Bulletin of Experimental Biology and Medicine, 85(4), 495-497. https://doi.org/10.1007/BF00801994

Vancouver

Klimovich VB, Samoilovich MP. Autoaggressive immunocompetent cells in mice in the late stages after irradiation. Bulletin of Experimental Biology and Medicine. 1978 Апр.;85(4):495-497. https://doi.org/10.1007/BF00801994

Author

Klimovich, V. B. ; Samoilovich, M. P. / Autoaggressive immunocompetent cells in mice in the late stages after irradiation. в: Bulletin of Experimental Biology and Medicine. 1978 ; Том 85, № 4. стр. 495-497.

BibTeX

@article{fec9ee4eeff341d0bfe6f18378419149,
title = "Autoaggressive immunocompetent cells in mice in the late stages after irradiation",
abstract = "Lethally irradiated DBA/1 or (C57BL×DBA/1)F1 mice were injected simultaneously with therapeutically effective doses of isologous bone marrow cells and syngeneic lymphocytes from intact mice (control) or from animals surviving different lengths of time after sublethal irradition. In the control the presence of lymphocytes in the mixed graft did not affect the survival rate of the recipients. Lymphocytes from mice surviving 6-12 months after irradiation in a dose of 600-700 R blocked the therapeutic effect of bone marrow (the killing effect). The intensity of the killing effect depended on the number of lymphocytes transplanted and the number of bone marrow cells in the graft. No killing effect was found if mice surviving 1 month after irradiation were used as donors of the lymphocytes. The results are regarded as evidence of autosensitization of the animal in the late stages after irradiation.",
keywords = "autoimmunity, late effects of irradiation, lymphocytes, transplantation of bone marrow",
author = "Klimovich, {V. B.} and Samoilovich, {M. P.}",
year = "1978",
month = apr,
doi = "10.1007/BF00801994",
language = "English",
volume = "85",
pages = "495--497",
journal = "Bulletin of Experimental Biology and Medicine",
issn = "0007-4888",
publisher = "Springer Nature",
number = "4",

}

RIS

TY - JOUR

T1 - Autoaggressive immunocompetent cells in mice in the late stages after irradiation

AU - Klimovich, V. B.

AU - Samoilovich, M. P.

PY - 1978/4

Y1 - 1978/4

N2 - Lethally irradiated DBA/1 or (C57BL×DBA/1)F1 mice were injected simultaneously with therapeutically effective doses of isologous bone marrow cells and syngeneic lymphocytes from intact mice (control) or from animals surviving different lengths of time after sublethal irradition. In the control the presence of lymphocytes in the mixed graft did not affect the survival rate of the recipients. Lymphocytes from mice surviving 6-12 months after irradiation in a dose of 600-700 R blocked the therapeutic effect of bone marrow (the killing effect). The intensity of the killing effect depended on the number of lymphocytes transplanted and the number of bone marrow cells in the graft. No killing effect was found if mice surviving 1 month after irradiation were used as donors of the lymphocytes. The results are regarded as evidence of autosensitization of the animal in the late stages after irradiation.

AB - Lethally irradiated DBA/1 or (C57BL×DBA/1)F1 mice were injected simultaneously with therapeutically effective doses of isologous bone marrow cells and syngeneic lymphocytes from intact mice (control) or from animals surviving different lengths of time after sublethal irradition. In the control the presence of lymphocytes in the mixed graft did not affect the survival rate of the recipients. Lymphocytes from mice surviving 6-12 months after irradiation in a dose of 600-700 R blocked the therapeutic effect of bone marrow (the killing effect). The intensity of the killing effect depended on the number of lymphocytes transplanted and the number of bone marrow cells in the graft. No killing effect was found if mice surviving 1 month after irradiation were used as donors of the lymphocytes. The results are regarded as evidence of autosensitization of the animal in the late stages after irradiation.

KW - autoimmunity

KW - late effects of irradiation

KW - lymphocytes

KW - transplantation of bone marrow

UR - http://www.scopus.com/inward/record.url?scp=0018178359&partnerID=8YFLogxK

U2 - 10.1007/BF00801994

DO - 10.1007/BF00801994

M3 - Article

AN - SCOPUS:0018178359

VL - 85

SP - 495

EP - 497

JO - Bulletin of Experimental Biology and Medicine

JF - Bulletin of Experimental Biology and Medicine

SN - 0007-4888

IS - 4

ER -

ID: 89782326