Assembling short reads from jumping libraries with large insert sizes

I. Vasilinetc, A.D. Prjibelski, A. Gurevich, A. Korobeynikov, P.A. Pevzner

Результат исследований: Научные публикации в периодических изданияхстатья

9 Цитирования (Scopus)

Выдержка

Motivation: Advances in Next-Generation Sequencing technologies and sample preparation recently enabled generation of high-quality jumping libraries that have a potential to significantly improve short read assemblies. However, assembly algorithms have to catch up with experimental innovations to benefit from them and to produce high-quality assemblies.Results: We present a new algorithm that extends recently described EXSPANDER universal repeat resolution approach to enable its applications to several challenging data types, including jumping libraries generated by the recently developed Illumina Nextera Mate Pair protocol. We demonstrate that, with these improvements, bacterial genomes often can be assembled in a few contigs using only a single Nextera Mate Pair library of short reads.
Язык оригиналаанглийский
Страницы (с-по)3262-3268
ЖурналBioinformatics
Том31
Номер выпуска20
DOI
СостояниеОпубликовано - 2015

Отпечаток

Libraries
Bacterial Genomes
Sequencing
Preparation
Genome
Genes
Innovation
Technology
Demonstrate

Цитировать

Vasilinetc, I. ; Prjibelski, A.D. ; Gurevich, A. ; Korobeynikov, A. ; Pevzner, P.A. / Assembling short reads from jumping libraries with large insert sizes. В: Bioinformatics. 2015 ; Том 31, № 20. стр. 3262-3268.
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Vasilinetc, I, Prjibelski, AD, Gurevich, A, Korobeynikov, A & Pevzner, PA 2015, 'Assembling short reads from jumping libraries with large insert sizes', Bioinformatics, том. 31, № 20, стр. 3262-3268. https://doi.org/10.1093/bioinformatics/btv337

Assembling short reads from jumping libraries with large insert sizes. / Vasilinetc, I.; Prjibelski, A.D.; Gurevich, A.; Korobeynikov, A.; Pevzner, P.A.

В: Bioinformatics, Том 31, № 20, 2015, стр. 3262-3268.

Результат исследований: Научные публикации в периодических изданияхстатья

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