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Генотоксический эффект действия иммобилизации и феромонального стрессора в соматических и половых клетках самцов мышей Mus musculus L. / Shcherbinina, Veronika D.; Petrova, Marina V.; Glinin, Timofey S.; Daev, Eugene V.

в: Ecological Genetics, Том 19, № 2, 27.07.2021, стр. 169-179.

Результаты исследований: Научные публикации в периодических изданияхстатьяРецензирование

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@article{0f579f65515944c498addf07c82586db,
title = "Генотоксический эффект действия иммобилизации и феромонального стрессора в соматических и половых клетках самцов мышей Mus musculus L.",
abstract = "BACKGROUND: Different stressors affect the genome integrity, but the mechanisms of such action are underexplored. MATERIALS AND METHODS: Bone marrow and testicular cells of CBA and CD-1 mouse males were used to estimate their genome integrity after stressor action by the comet assay. RESULTS: It is shown here that restraint and 2,5-dimethylpyrazine both increase damaged cell frequency in bone marrow as well as in testes of mouse males. For the first time the effect of immobilization and 2,5-dimethylpyrazine in testicular cells is demonstrated using the comet assay. Both stressors have similar effects in cells of both tissues analyzed. CONCLUSION: Mechanisms of the effects and possible role in microevolution are under discussion.",
keywords = "2,5-dimethylpyrazine, Bone marrow, Comet assay, Genome, Mouse, Pheromone, Restraint, Stress, Testes, 2,5-dimethylpyrazine, Bone marrow, Comet assay, Genome, Mouse, Pheromone, Restraint, Stress, Testes",
author = "Shcherbinina, {Veronika D.} and Petrova, {Marina V.} and Glinin, {Timofey S.} and Daev, {Eugene V.}",
note = "Publisher Copyright: {\textcopyright} Eco-Vector, 2021",
year = "2021",
month = jul,
day = "27",
doi = "10.17816/ECOGEN65208",
language = "русский",
volume = "19",
pages = "169--179",
journal = "ЭКОЛОГИЧЕСКАЯ ГЕНЕТИКА",
issn = "1811-0932",
publisher = "Эко-Вектор",
number = "2",

}

RIS

TY - JOUR

T1 - Генотоксический эффект действия иммобилизации и феромонального стрессора в соматических и половых клетках самцов мышей Mus musculus L.

AU - Shcherbinina, Veronika D.

AU - Petrova, Marina V.

AU - Glinin, Timofey S.

AU - Daev, Eugene V.

N1 - Publisher Copyright: © Eco-Vector, 2021

PY - 2021/7/27

Y1 - 2021/7/27

N2 - BACKGROUND: Different stressors affect the genome integrity, but the mechanisms of such action are underexplored. MATERIALS AND METHODS: Bone marrow and testicular cells of CBA and CD-1 mouse males were used to estimate their genome integrity after stressor action by the comet assay. RESULTS: It is shown here that restraint and 2,5-dimethylpyrazine both increase damaged cell frequency in bone marrow as well as in testes of mouse males. For the first time the effect of immobilization and 2,5-dimethylpyrazine in testicular cells is demonstrated using the comet assay. Both stressors have similar effects in cells of both tissues analyzed. CONCLUSION: Mechanisms of the effects and possible role in microevolution are under discussion.

AB - BACKGROUND: Different stressors affect the genome integrity, but the mechanisms of such action are underexplored. MATERIALS AND METHODS: Bone marrow and testicular cells of CBA and CD-1 mouse males were used to estimate their genome integrity after stressor action by the comet assay. RESULTS: It is shown here that restraint and 2,5-dimethylpyrazine both increase damaged cell frequency in bone marrow as well as in testes of mouse males. For the first time the effect of immobilization and 2,5-dimethylpyrazine in testicular cells is demonstrated using the comet assay. Both stressors have similar effects in cells of both tissues analyzed. CONCLUSION: Mechanisms of the effects and possible role in microevolution are under discussion.

KW - 2,5-dimethylpyrazine

KW - Bone marrow

KW - Comet assay

KW - Genome

KW - Mouse

KW - Pheromone

KW - Restraint

KW - Stress

KW - Testes

KW - 2,5-dimethylpyrazine

KW - Bone marrow

KW - Comet assay

KW - Genome

KW - Mouse

KW - Pheromone

KW - Restraint

KW - Stress

KW - Testes

UR - http://www.scopus.com/inward/record.url?scp=85113189946&partnerID=8YFLogxK

UR - https://www.mendeley.com/catalogue/ac3379e1-84d7-330a-ab23-4ebb62932d87/

U2 - 10.17816/ECOGEN65208

DO - 10.17816/ECOGEN65208

M3 - статья

AN - SCOPUS:85113189946

VL - 19

SP - 169

EP - 179

JO - ЭКОЛОГИЧЕСКАЯ ГЕНЕТИКА

JF - ЭКОЛОГИЧЕСКАЯ ГЕНЕТИКА

SN - 1811-0932

IS - 2

ER -

ID: 85274509