Лекарственные поражения печени у онкологических пациентов

V. T. Ivashkin; K. L. Raikhelson; L. K. Palgova; M. V. Maevskaya; O. A. Gerasimova; E. A. Kondrashina; N. V. Marchenko; A. Yu Baranovsky

doi:10.17650/1818-8346-2020-15-3-107-127

Лекарственные поражения печени у онкологических пациентов

V. T. Ivashkin, K. L. Raikhelson, L. K. Palgova, M. V. Maevskaya, O. A. Gerasimova, E. A. Kondrashina, N. V. Marchenko, A. Yu Baranovsky

Научно-клинический и образовательный центр гастроэнтерологии и гепатологии

Результат исследований: Научные публикации в периодических изданиях › статья › рецензирование

Аннотация

This review includes information about epidemiological data, development feature, phenotypes, principles of classification, diagnosis, and prognosis for drug-induced liver injury (DILI). Actual clinical recommendations regarding management of the DILI arising in the chemotherapy of cancer discussed. Drugs that can influence on individual pathogenetic mechanisms of growth and symptoms DILI are considered. Clinical studies for the prophylaxis and treatment of DILI associated with anticancer chemotherapy analyzed in detail. The prevention and treatment regimens for DILI in patients receiving chemotherapy and immunotherapy various localizations of cancer given both in research and in practical recommendations.

Переведенное название	Drug-induced liver injury in cancer patients
Язык оригинала	русский
Страницы (с-по)	80-94
Число страниц	15
Журнал	Oncogematologiya
Том	15
Номер выпуска	3
DOI	https://doi.org/10.17650/1818-8346-2020-15-3-107-127
Состояние	Опубликовано - 2020

Предметные области Scopus

Гематология
Онкология

Ключевые слова

Bicyclol
Cancer
Checkpoint inhibitor
Chemotherapy
Drug-induced liver injury
Essential phospholipid
Glucocorticosteroids
Hepatotoxicity
N-acetylcysteine
S-аdenosylmethionine

Доступ к документу

10.17650/1818-8346-2020-15-3-107-127

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abstract = "This review includes information about epidemiological data, development feature, phenotypes, principles of classification, diagnosis, and prognosis for drug-induced liver injury (DILI). Actual clinical recommendations regarding management of the DILI arising in the chemotherapy of cancer discussed. Drugs that can influence on individual pathogenetic mechanisms of growth and symptoms DILI are considered. Clinical studies for the prophylaxis and treatment of DILI associated with anticancer chemotherapy analyzed in detail. The prevention and treatment regimens for DILI in patients receiving chemotherapy and immunotherapy various localizations of cancer given both in research and in practical recommendations.",

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Лекарственные поражения печени у онкологических пациентов. / Ivashkin, V. T.; Raikhelson, K. L.; Palgova, L. K.; Maevskaya, M. V.; Gerasimova, O. A.; Kondrashina, E. A.; Marchenko, N. V.; Baranovsky, A. Yu.

В: Oncogematologiya, Том 15, № 3, 2020, стр. 80-94.

Результат исследований: Научные публикации в периодических изданиях › статья › рецензирование

TY - JOUR

T1 - Лекарственные поражения печени у онкологических пациентов

AU - Ivashkin, V. T.

AU - Raikhelson, K. L.

AU - Palgova, L. K.

AU - Maevskaya, M. V.

AU - Gerasimova, O. A.

AU - Kondrashina, E. A.

AU - Marchenko, N. V.

AU - Baranovsky, A. Yu

PY - 2020

Y1 - 2020

N2 - This review includes information about epidemiological data, development feature, phenotypes, principles of classification, diagnosis, and prognosis for drug-induced liver injury (DILI). Actual clinical recommendations regarding management of the DILI arising in the chemotherapy of cancer discussed. Drugs that can influence on individual pathogenetic mechanisms of growth and symptoms DILI are considered. Clinical studies for the prophylaxis and treatment of DILI associated with anticancer chemotherapy analyzed in detail. The prevention and treatment regimens for DILI in patients receiving chemotherapy and immunotherapy various localizations of cancer given both in research and in practical recommendations.

AB - This review includes information about epidemiological data, development feature, phenotypes, principles of classification, diagnosis, and prognosis for drug-induced liver injury (DILI). Actual clinical recommendations regarding management of the DILI arising in the chemotherapy of cancer discussed. Drugs that can influence on individual pathogenetic mechanisms of growth and symptoms DILI are considered. Clinical studies for the prophylaxis and treatment of DILI associated with anticancer chemotherapy analyzed in detail. The prevention and treatment regimens for DILI in patients receiving chemotherapy and immunotherapy various localizations of cancer given both in research and in practical recommendations.

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KW - Chemotherapy

KW - Drug-induced liver injury

KW - Essential phospholipid

KW - Glucocorticosteroids

KW - Hepatotoxicity

KW - N-acetylcysteine

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M3 - статья

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