Phosphocreatine immobilization of the surface of silica and magnetite nanoparticles for targeted drug delivery

Переведенное название: Исследование возможности иммобилизации фосфокреатина на поверхности наночастиц кремнезема и магнетита для таргетной доставки

D. V. Korolev, N.V. Evreinova, E.V. Zakharova, Kamil G. Gareev, Елена Борисовна Наумышева, D.V. Postnov, Виктор Николаевич Постнов, M.M. Galagudza

Результат исследований: Научные публикации в периодических изданияхстатья

Выдержка

A method is proposed for immobilization of anti-ischemic drug phosphocreatine on the
surface of aminated silica and magnetite nanoparticles of similar size and shape. The synthesis
of spacer and the coordination-ionic drug immobilization technique are described. Magnetite
nanoparticles demonstrated much more effi cient chemisorption of phosphocreatine than silica
nanoparticles. The method was recommended for practical application.
Язык оригиналаанглийский
Номер статьи5
Страницы (с-по)1096-1101
Число страниц6
ЖурналRussian Chemical Bulletin
Том68
Номер выпуска5
СостояниеОпубликовано - 2019

Отпечаток

Magnetite Nanoparticles
Phosphocreatine
Silicon Dioxide
Ionic drugs
Chemisorption
Nanoparticles
Pharmaceutical Preparations
Targeted drug delivery

Ключевые слова

  • magnetite nanoparticles
  • silica nanoparticles
  • amination
  • phosphocreatine
  • immo bilization

Цитировать

Korolev, D. V., Evreinova, N. V., Zakharova, E. V., Gareev, K. G., Наумышева, Е. Б., Postnov, D. V., ... Galagudza, M. M. (2019). Phosphocreatine immobilization of the surface of silica and magnetite nanoparticles for targeted drug delivery. Russian Chemical Bulletin, 68(5), 1096-1101. [5].
Korolev, D. V. ; Evreinova, N.V. ; Zakharova, E.V. ; Gareev, Kamil G. ; Наумышева, Елена Борисовна ; Postnov, D.V. ; Постнов, Виктор Николаевич ; Galagudza, M.M. / Phosphocreatine immobilization of the surface of silica and magnetite nanoparticles for targeted drug delivery. В: Russian Chemical Bulletin. 2019 ; Том 68, № 5. стр. 1096-1101.
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abstract = "A method is proposed for immobilization of anti-ischemic drug phosphocreatine on the surface of aminated silica and magnetite nanoparticles of similar size and shape. The synthesis of spacer and the coordination-ionic drug immobilization technique are described. Magnetite nanoparticles demonstrated much more efficient chemisorption of phosphocreatine than silica nanoparticles. The method was recommended for practical application.",
keywords = "magnetite nanoparticles, silica nanoparticles, amination, phosphocreatine, immo bilization, magnetite nanoparticles, silica nanoparticles, amination, phosphocreatine, immobilization",
author = "Korolev, {D. V.} and N.V. Evreinova and E.V. Zakharova and Gareev, {Kamil G.} and Наумышева, {Елена Борисовна} and D.V. Postnov and Постнов, {Виктор Николаевич} and M.M. Galagudza",
year = "2019",
language = "English",
volume = "68",
pages = "1096--1101",
journal = "Russian Chemical Bulletin",
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Korolev, DV, Evreinova, NV, Zakharova, EV, Gareev, KG, Наумышева, ЕБ, Postnov, DV, Постнов, ВН & Galagudza, MM 2019, 'Phosphocreatine immobilization of the surface of silica and magnetite nanoparticles for targeted drug delivery', Russian Chemical Bulletin, том. 68, № 5, 5, стр. 1096-1101.

Phosphocreatine immobilization of the surface of silica and magnetite nanoparticles for targeted drug delivery. / Korolev, D. V.; Evreinova, N.V.; Zakharova, E.V.; Gareev, Kamil G.; Наумышева, Елена Борисовна; Postnov, D.V.; Постнов, Виктор Николаевич; Galagudza, M.M.

В: Russian Chemical Bulletin, Том 68, № 5, 5, 2019, стр. 1096-1101.

Результат исследований: Научные публикации в периодических изданияхстатья

TY - JOUR

T1 - Phosphocreatine immobilization of the surface of silica and magnetite nanoparticles for targeted drug delivery

AU - Korolev, D. V.

AU - Evreinova, N.V.

AU - Zakharova, E.V.

AU - Gareev, Kamil G.

AU - Наумышева, Елена Борисовна

AU - Postnov, D.V.

AU - Постнов, Виктор Николаевич

AU - Galagudza, M.M.

PY - 2019

Y1 - 2019

N2 - A method is proposed for immobilization of anti-ischemic drug phosphocreatine on the surface of aminated silica and magnetite nanoparticles of similar size and shape. The synthesis of spacer and the coordination-ionic drug immobilization technique are described. Magnetite nanoparticles demonstrated much more efficient chemisorption of phosphocreatine than silica nanoparticles. The method was recommended for practical application.

AB - A method is proposed for immobilization of anti-ischemic drug phosphocreatine on the surface of aminated silica and magnetite nanoparticles of similar size and shape. The synthesis of spacer and the coordination-ionic drug immobilization technique are described. Magnetite nanoparticles demonstrated much more efficient chemisorption of phosphocreatine than silica nanoparticles. The method was recommended for practical application.

KW - magnetite nanoparticles

KW - silica nanoparticles

KW - amination

KW - phosphocreatine

KW - immo bilization

KW - magnetite nanoparticles

KW - silica nanoparticles

KW - amination

KW - phosphocreatine

KW - immobilization

M3 - Article

VL - 68

SP - 1096

EP - 1101

JO - Russian Chemical Bulletin

JF - Russian Chemical Bulletin

SN - 1066-5285

IS - 5

M1 - 5

ER -

Korolev DV, Evreinova NV, Zakharova EV, Gareev KG, Наумышева ЕБ, Postnov DV и соавт. Phosphocreatine immobilization of the surface of silica and magnetite nanoparticles for targeted drug delivery. Russian Chemical Bulletin. 2019;68(5):1096-1101. 5.