Ugnetenie merkuzalom i étakrinovoǐ kislotoǐ khlornoǐ pronitsaemosti i transporta natriia v kozhe liagushkhi.

E. A. Lavrova, I. V. Natochin

Research output

1 Citation (Scopus)

Abstract

Potential difference across the frog skin is increased 1-2 min after addition of 0.063-1.0 mg/ml ethacrynic acid or 0.2-1.0 mg/ml mercusal to outside Ringer solution. Within this time the short-circuit current remains unchanged or increased. Potential difference and short-circuit current are diminished after the addition of ethacrynic acid or mercusal to inside solution. This effect is similar to that of ouabain. These findings suggest that ethacrynic acid and mercusal inhibit chloride channel in the apical cell membrane, and inhibit sodium transport in the basolateral membrane.

Original languageRussian
Pages (from-to)651-656
Number of pages6
JournalBiofizika
Volume26
Issue number4
Publication statusPublished - 1 Jul 1981

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Scopus subject areas

  • Biophysics

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