The role of Dm NXF1 in controlling early embryonic mitoses in drosophila melanogaster

Research outputpeer-review

1 Citation (Scopus)

Abstract

The known function of the evolutionary conservative NXF1 (Nuclear eXport Factor) is the nuclear-cytoplasmic transport of the most mRNAs. On our data Dm NXF1 is involved in control of cell division. By immunostaining of early embryos with antibodies to C-terminal part of Dm NXF1 we have shown that the intensity of the staining depends on the cell cycle stage. The cytoplasmic Dm NXF1 is abundant on prometaphase and it almost disappears on anaphase. It is possible that Dm NXF1 can be involved in RNP-complexes including mRNAs which translation is regulated during cell cycle. Such complexes dissociate to resolve the translation of according mRNAs.

Original languageEnglish
Title of host publicationEncyclopedia of Cell Biology Research
PublisherNova Science Publishers, Inc.
Pages543-549
Number of pages7
ISBN (Print)9781613240021
Publication statusPublished - 1 Mar 2012

Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

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