The formation of calcium and magnesium phosphates of the renal stones depending on the composition of the crystallization medium

Mariya A. Kuz’mina, Anton M. Nikolaev, Olga V. Frank-Kamenetskaya

Research outputpeer-review

Abstract

The study of the phase formation of phosphates in the solutions simulating the normal inorganic composition of human urine was carried out by the precipitation method. All calcium and magnesium phosphates typical for the kidney stones were synthesized: brushite, octacalcium phosphate, hydroxyapatite, struvite and Mg-whitlockite. The regularities of the calcium and magnesium phosphates formation in the crystallization medium of variable composition were found out. The borders of the crystallization areas of the synthesized phases were determined in the axes «initial pH value—main components’ concentration». In general, phosphates crystallization areas are defined by the starting concentrations of the main components, pH value of the crystallization medium and by the presence of the additional ions in the solution. It was shown that crystallization of any calcium phosphate leads to the significant decreasing of the pH value of the crystallization medium. Adding of the inorganic components typical for the human urine into the Ca–PO4 system leads to the moving of the crystallization area borders of the calcium phosphates (brushite, octacalcium phosphate, apatite). Crystallization doesn’t occur in the areas that are characterized by the composition and pH typical for the normal human urine. Increasing amount of the precursors or pH values leads to the start of the phosphate crystallization.

Original languageEnglish
Title of host publicationProcesses and Phenomena on the Boundary Between Biogenic and Abiogenic Nature
Subtitle of host publicationConference proceedings
EditorsOlga V. Frank-Kamenetskaya, Dmitry Yu. Vlasov, Elena G. Panova, Sofia N. Lessovaia
Place of PublicationCham
PublisherSpringer
Pages107-118
Number of pages12
ISBN (Electronic)9783030216146
ISBN (Print)9783030216139
DOIs
Publication statusPublished - 2020
EventVI International Symposium "Biogenic-abiogenic interactions in natural and anthropogenic systems" devoted to the 150th anniversary of the Saint Petersburg Naturalists Society - СПбГУ, Санкт-Петербург
Duration: 24 Sep 201827 Sep 2018
Conference number: VI

Publication series

NameLecture Notes in Earth System Sciences
ISSN (Print)2193-8571
ISSN (Electronic)2193-858X

Conference

ConferenceVI International Symposium "Biogenic-abiogenic interactions in natural and anthropogenic systems" devoted to the 150th anniversary of the Saint Petersburg Naturalists Society
CountryRussian Federation
CityСанкт-Петербург
Period24/09/1827/09/18

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Scopus subject areas

  • Computers in Earth Sciences
  • Earth and Planetary Sciences(all)

Cite this

Kuz’mina, M. A., Nikolaev, A. M., & Frank-Kamenetskaya, O. V. (2020). The formation of calcium and magnesium phosphates of the renal stones depending on the composition of the crystallization medium. In O. V. Frank-Kamenetskaya, D. Y. Vlasov, E. G. Panova, & S. N. Lessovaia (Eds.), Processes and Phenomena on the Boundary Between Biogenic and Abiogenic Nature: Conference proceedings (pp. 107-118). (Lecture Notes in Earth System Sciences). Cham: Springer. https://doi.org/10.1007/978-3-030-21614-6_6