The effect of denervation on the histone composition in skeletal muscle nuclei

V. S. Gurevich, N. I. Razumovskaya

Research output: Contribution to journalArticlepeer-review

Abstract

Three days after denervation of the gastrocnemius muscle of rabbits the histone DNA ratio increases 40% in muscle cell nuclei. Electrophoresis of the histones in starch gel showed that the increase is due to an increase in fraction F2al. After a tenotomy the proportion of the histone fractions remained the same as in an intact muscle. A theory is advanced concerning the possible regulatory effect of nerve impulsation on processes occurring at the level of nuclear structures.

Original languageEnglish
Pages (from-to)493-495
Number of pages3
JournalBiochemistry (Moscow)
Volume38
Issue number3 II
StatePublished - 1 Jan 1973

Scopus subject areas

  • Biochemistry

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