The central nervous system of mammals acts as a mutagenic/anti-mutagenic factor: role in microevolution

Research output

1 Citation (Scopus)

Abstract

The purpose of this study is to show a bidirectional influence of the mouse pheromones on the genome stability of germ and somatic target cells in conspecific recipients. Using unidentified mixture of pheromones originated from adult animals (males or females) it was revealed that these chemosignals can modify frequencies of different chromosomal disturbances in mitotic and meiotic dividing cells. This finding is important to understand the mechanisms of self-regulation and microevolutionary processes in mouse populations. It can also expand our understanding of the role of the central nervous system and the pathways from the environment to the cell genomes and back to the whole organism and populations in the regulation of the microevolutionary changes in mammals.
Original languageEnglish
Title of host publicationGenetics, Evolution and Radiation
PublisherSpringer
Pages487-495
ISBN (Print)978-3-319-48837-0; 978-3-319-48838-7
DOIs
Publication statusPublished - 2017

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Mammals
Central Nervous System
Pheromones
Population
Genome

Cite this

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abstract = "The purpose of this study is to show a bidirectional influence of the mouse pheromones on the genome stability of germ and somatic target cells in conspecific recipients. Using unidentified mixture of pheromones originated from adult animals (males or females) it was revealed that these chemosignals can modify frequencies of different chromosomal disturbances in mitotic and meiotic dividing cells. This finding is important to understand the mechanisms of self-regulation and microevolutionary processes in mouse populations. It can also expand our understanding of the role of the central nervous system and the pathways from the environment to the cell genomes and back to the whole organism and populations in the regulation of the microevolutionary changes in mammals.",
keywords = "Nervous system - House mouse - Pheromones - Chromosome aberrations - Spermatocytes - Bone marrow -Genome integrity",
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The central nervous system of mammals acts as a mutagenic/anti-mutagenic factor: role in microevolution. / Daev, E.V.

Genetics, Evolution and Radiation. Springer, 2017. p. 487-495.

Research output

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