Research output: Contribution to journal › Article › peer-review
An investigation of the reaction of 1-lithio-1,3-diynes, generated in situ, with nitriles has been carried out. In the case of aromatic nitriles 1-arylalk-1-ene-3,5-diynylamines are formed, which undergo dimerization and cyclization on isolation, giving 3-(alka-1,3-diynyl)-4-(alk-2-ynyl)-2,6- diarylpyridines. The effect of the nature of the substituent in the benzonitrile molecule on the selectivity of the reaction and the yield of the products has been determined. A scheme is proposed for the conversions and the structures of the intermediates have been established.
Original language | English |
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Pages (from-to) | 615-624 |
Number of pages | 10 |
Journal | Chemistry of Heterocyclic Compounds |
Volume | 42 |
Issue number | 5 |
DOIs | |
State | Published - 1 May 2006 |
ID: 33788663